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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT74 All Species: 25.76
Human Site: S153 Identified Species: 80.95
UniProt: Q7RTS7 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTS7 NP_778223.2 529 57865 S153 V L N D K F A S F I D K V R F
Chimpanzee Pan troglodytes A5A6M6 637 65471 S188 S L N N Q F A S F I D K V R F
Rhesus Macaque Macaca mulatta XP_001097399 529 57855 S153 A L N D K F A S F I D K V R F
Dog Lupus familis XP_543647 619 67268 S239 A L N N K F A S F I D K V R F
Cat Felis silvestris
Mouse Mus musculus Q9R0H5 524 57364 S144 A L N N K F A S F I D K V R F
Rat Rattus norvegicus Q6IG03 553 60368 S144 A L N N K F A S F I D K V R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521394 720 77473 S161 V L N N K F A S F I D K V R F
Chicken Gallus gallus O93532 492 53785 E136 I D K V R F L E Q Q N K M L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.9 95.2 71.4 N.A. 72 68.9 N.A. 59.5 51.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.7 97.3 76.2 N.A. 81 78.3 N.A. 65.2 68.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 93.3 86.6 N.A. 86.6 86.6 N.A. 93.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 100 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 0 88 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 25 0 0 0 0 0 0 88 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 100 0 0 88 0 0 0 0 0 88 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 0 0 0 0 0 88 0 0 0 0 0 % I
% Lys: 0 0 13 0 75 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 0 88 0 0 0 0 13 0 0 0 0 0 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 88 63 0 0 0 0 0 0 13 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 13 13 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 0 0 0 88 0 % R
% Ser: 13 0 0 0 0 0 0 88 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 25 0 0 13 0 0 0 0 0 0 0 0 88 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _