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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT74
All Species:
20.91
Human Site:
S462
Identified Species:
65.71
UniProt:
Q7RTS7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTS7
NP_778223.2
529
57865
S462
G
E
N
P
S
S
V
S
I
S
V
I
S
S
S
Chimpanzee
Pan troglodytes
A5A6M6
637
65471
G497
G
E
C
A
P
N
V
G
V
S
V
S
T
S
H
Rhesus Macaque
Macaca mulatta
XP_001097399
529
57855
S462
G
E
N
P
S
S
V
S
I
S
V
I
S
S
S
Dog
Lupus familis
XP_543647
619
67268
S548
G
E
N
P
S
S
V
S
I
S
V
I
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0H5
524
57364
S453
G
E
Y
S
S
P
V
S
I
S
I
I
S
S
T
Rat
Rattus norvegicus
Q6IG03
553
60368
S453
G
E
H
T
N
A
V
S
I
S
V
I
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521394
720
77473
S470
G
E
N
P
S
S
V
S
I
S
V
I
S
S
G
Chicken
Gallus gallus
O93532
492
53785
K416
I
E
I
A
T
Y
R
K
L
L
E
G
E
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.9
95.2
71.4
N.A.
72
68.9
N.A.
59.5
51.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.7
97.3
76.2
N.A.
81
78.3
N.A.
65.2
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
93.3
N.A.
66.6
73.3
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
93.3
N.A.
80
93.3
N.A.
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
13
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
100
0
0
0
0
0
0
0
0
13
0
13
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
88
0
0
0
0
0
0
13
0
0
0
13
0
0
25
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
13
0
13
0
0
0
0
0
75
0
13
75
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
0
13
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
13
13
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
63
50
0
75
0
88
0
13
75
88
50
% S
% Thr:
0
0
0
13
13
0
0
0
0
0
0
0
13
0
13
% T
% Val:
0
0
0
0
0
0
88
0
13
0
75
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _