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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYM All Species: 25.76
Human Site: S513 Identified Species: 51.52
UniProt: Q7RTS9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTS9 NP_060123.3 669 75935 S513 S L R G S L S S N D V P L P D
Chimpanzee Pan troglodytes XP_512125 656 73923 S513 S L R G S L S S N D V P L P D
Rhesus Macaque Macaca mulatta XP_001088281 624 70544 F489 A Q R I I S L F S L L S K K H
Dog Lupus familis XP_537347 669 75860 S513 S L R G S L S S N D V P L P D
Cat Felis silvestris
Mouse Mus musculus Q8CHY3 669 75830 S513 S L R G P L S S S D V P L P D
Rat Rattus norvegicus B4F766 674 76473 S518 S L R G S L S S S D V P L P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLW3 669 76142 S513 S L R G S L D S N D S P L P D
Frog Xenopus laevis Q6DCP6 669 76102 S513 S L R G S L G S D E S P L P D
Zebra Danio Brachydanio rerio XP_701125 523 59248 E388 L E I L Y H V E E R N S H H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KNA0 699 79106 V539 P A D S A V F V N V S T T P E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496492 689 78184 D536 S S Q N D V A D G Q P I N F H
Sea Urchin Strong. purpuratus XP_783417 689 79186 G526 S S A L E P N G D L T Q D A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 85.9 97.7 N.A. 94.7 93.1 N.A. N.A. 88 82.3 58.1 N.A. 41.6 N.A. 36.4 50.6
Protein Similarity: 100 95.2 88.6 99 N.A. 97.3 96.1 N.A. N.A. 94 91.4 68 N.A. 61 N.A. 56.3 70.1
P-Site Identity: 100 100 6.6 100 N.A. 86.6 93.3 N.A. N.A. 86.6 73.3 0 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 100 N.A. N.A. 86.6 86.6 0 N.A. 33.3 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 0 9 0 9 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 0 9 9 17 50 0 0 9 0 59 % D
% Glu: 0 9 0 0 9 0 0 9 9 9 0 0 0 0 17 % E
% Phe: 0 0 0 0 0 0 9 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 59 0 0 9 9 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 9 9 17 % H
% Ile: 0 0 9 9 9 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % K
% Leu: 9 59 0 17 0 59 9 0 0 17 9 0 59 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 42 0 9 0 9 0 0 % N
% Pro: 9 0 0 0 9 9 0 0 0 0 9 59 0 67 0 % P
% Gln: 0 9 9 0 0 0 0 0 0 9 0 9 0 0 0 % Q
% Arg: 0 0 67 0 0 0 0 0 0 9 0 0 0 0 0 % R
% Ser: 75 17 0 9 50 9 42 59 25 0 25 17 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % T
% Val: 0 0 0 0 0 17 9 9 0 9 42 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _