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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL5
All Species:
10.91
Human Site:
S259
Identified Species:
34.29
UniProt:
Q7RTU5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTU5
XP_001719373
278
29462
S259
P
S
S
L
V
P
E
S
S
E
S
S
C
F
S
Chimpanzee
Pan troglodytes
XP_001138637
276
29285
S257
P
S
S
L
V
P
E
S
S
E
S
S
C
F
S
Rhesus Macaque
Macaca mulatta
XP_001099365
276
29624
S257
P
S
S
L
V
P
E
S
S
E
S
S
C
F
S
Dog
Lupus familis
XP_850183
156
17406
E138
R
Y
I
K
Y
L
Q
E
L
L
S
A
A
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJR7
174
20227
K156
Y
P
D
E
S
E
T
K
K
N
P
R
T
A
S
Rat
Rattus norvegicus
Q64305
326
35287
S266
G
T
R
S
P
S
P
S
D
P
D
Y
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506058
402
43481
E382
V
S
S
S
S
A
P
E
S
S
S
P
S
R
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10007
268
30806
S248
F
N
G
F
Q
E
E
S
E
G
N
I
L
I
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
86.6
41.3
N.A.
32
22.3
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
100
92.8
89.2
45.6
N.A.
41
32.8
N.A.
47
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
6.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
0
0
0
0
13
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
13
0
13
0
0
0
13
% D
% Glu:
0
0
0
13
0
25
50
25
13
38
0
0
0
0
0
% E
% Phe:
13
0
0
13
0
0
0
0
0
0
0
0
0
38
13
% F
% Gly:
13
0
13
0
0
0
0
0
0
13
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
13
0
13
13
% I
% Lys:
0
0
0
13
0
0
0
13
13
0
0
0
0
0
0
% K
% Leu:
0
0
0
38
0
13
0
0
13
13
0
0
13
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
13
13
0
0
0
0
% N
% Pro:
38
13
0
0
13
38
25
0
0
13
13
13
0
0
13
% P
% Gln:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
13
0
0
0
0
0
0
0
0
13
0
13
0
% R
% Ser:
0
50
50
25
25
13
0
63
50
13
63
38
13
0
50
% S
% Thr:
0
13
0
0
0
0
13
0
0
0
0
0
13
0
0
% T
% Val:
13
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
13
0
0
13
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _