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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASCL5 All Species: 8.04
Human Site: S273 Identified Species: 25.27
UniProt: Q7RTU5 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTU5 XP_001719373 278 29462 S273 S P S P F L E S E E S W H _ _
Chimpanzee Pan troglodytes XP_001138637 276 29285 S271 S R S P F L E S E E S C H _ _
Rhesus Macaque Macaca mulatta XP_001099365 276 29624 S271 S P S P F L E S E E S C H _ _
Dog Lupus familis XP_850183 156 17406
Cat Felis silvestris
Mouse Mus musculus Q9JJR7 174 20227
Rat Rattus norvegicus Q64305 326 35287 L280 P P L A G H S L S W A D E K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506058 402 43481 E396 F S S S P F C E S E E P S R _
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10007 268 30806 N262 D I S T F N F N S S N N A M _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 86.6 41.3 N.A. 32 22.3 N.A. 38.5 N.A. N.A. N.A. N.A. N.A. N.A. 26.6 N.A.
Protein Similarity: 100 92.8 89.2 45.6 N.A. 41 32.8 N.A. 47 N.A. N.A. N.A. N.A. N.A. N.A. 38.4 N.A.
P-Site Identity: 100 84.6 92.3 0 N.A. 0 6.6 N.A. 14.2 N.A. N.A. N.A. N.A. N.A. N.A. 14.2 N.A.
P-Site Similarity: 100 84.6 92.3 0 N.A. 0 13.3 N.A. 14.2 N.A. N.A. N.A. N.A. N.A. N.A. 28.5 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 0 0 0 0 13 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 13 0 0 0 0 25 0 0 0 % C
% Asp: 13 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % D
% Glu: 0 0 0 0 0 0 38 13 38 50 13 0 13 0 0 % E
% Phe: 13 0 0 0 50 13 13 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 38 0 0 % H
% Ile: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 13 0 0 38 0 13 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % M
% Asn: 0 0 0 0 0 13 0 13 0 0 13 13 0 0 0 % N
% Pro: 13 38 0 38 13 0 0 0 0 0 0 13 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % Q
% Arg: 0 13 0 0 0 0 0 0 0 0 0 0 0 13 0 % R
% Ser: 38 13 63 13 0 0 13 38 38 13 38 0 13 0 0 % S
% Thr: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 13 0 13 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 38 63 % _