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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf21 All Species: 24.24
Human Site: S139 Identified Species: 59.26
UniProt: Q7RTV5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTV5 NP_714542.1 226 24857 S139 K R G E E I A S S G Q S P H I
Chimpanzee Pan troglodytes XP_520707 226 24796 S139 K R G E E I A S S G Q S P H V
Rhesus Macaque Macaca mulatta XP_001106503 226 24905 S139 K R G E E I A S S G Q S P H V
Dog Lupus familis XP_848380 230 25077 S143 K R G E G I A S S G K S P H I
Cat Felis silvestris
Mouse Mus musculus Q9D1A0 226 24885 S139 K R G E E I S S S G Q S P H I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001092155 228 25580 S141 K K G E T S T S S G R S P H V
Zebra Danio Brachydanio rerio XP_002666723 223 25149 E135 R R G E T Y M E T P S V S P H
Tiger Blowfish Takifugu rubipres Q8AV19 226 25812 D138 K R E E T F T D S A Q P S P H
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326159 200 21723 S113 V Y A D P S H S S Y K A L Q F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZUU2 248 26586 T142 G S I D Q A N T F V E Q T K F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.4 86.9 N.A. 89.3 N.A. N.A. N.A. N.A. 58.7 54.8 54.4 N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 97.7 93.9 N.A. 94.6 N.A. N.A. N.A. N.A. 73.6 73 70.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 86.6 N.A. 93.3 N.A. N.A. N.A. N.A. 60 20 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 N.A. N.A. N.A. N.A. 80 33.3 33.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: 26.5 N.A. N.A. 26.6 N.A. N.A.
Protein Similarity: 43.3 N.A. N.A. 44.7 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 40 0 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 80 40 0 0 10 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 20 % F
% Gly: 10 0 70 0 10 0 0 0 0 60 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 60 20 % H
% Ile: 0 0 10 0 0 50 0 0 0 0 0 0 0 0 30 % I
% Lys: 70 10 0 0 0 0 0 0 0 0 20 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 10 0 10 60 20 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 50 10 0 10 0 % Q
% Arg: 10 70 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 10 0 0 0 20 10 70 80 0 10 60 20 0 0 % S
% Thr: 0 0 0 0 30 0 20 10 10 0 0 0 10 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _