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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOA
All Species:
13.64
Human Site:
S227
Identified Species:
60
UniProt:
Q7RTW8
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTW8
NP_733764.1
1153
128533
S227
Y
D
K
T
S
A
H
S
Q
R
A
L
Y
S
W
Chimpanzee
Pan troglodytes
XP_001151056
711
79720
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850839
1185
131563
S227
Y
D
Q
T
S
A
H
S
Q
R
A
L
Y
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8K561
1137
126412
T227
Y
D
Q
T
S
A
H
T
Q
R
A
L
Y
S
W
Rat
Rattus norvegicus
XP_574553
1137
126578
T227
Y
D
Q
T
S
A
H
T
Q
R
A
L
Y
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234949
998
111015
N138
A
S
W
V
S
A
E
N
L
W
I
L
G
R
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.1
N.A.
80.5
N.A.
76.3
77.7
N.A.
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.3
N.A.
87.5
N.A.
84.9
85.6
N.A.
N.A.
66.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
84
0
0
0
0
67
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
17
0
0
84
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
0
0
67
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
67
0
0
0
17
0
% R
% Ser:
0
17
0
0
84
0
0
34
0
0
0
0
0
67
0
% S
% Thr:
0
0
0
67
0
0
0
34
0
0
0
0
0
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
17
0
0
0
0
0
0
17
0
0
0
0
67
% W
% Tyr:
67
0
0
0
0
0
0
0
0
0
0
0
67
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _