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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTOA All Species: 13.64
Human Site: S227 Identified Species: 60
UniProt: Q7RTW8 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTW8 NP_733764.1 1153 128533 S227 Y D K T S A H S Q R A L Y S W
Chimpanzee Pan troglodytes XP_001151056 711 79720
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850839 1185 131563 S227 Y D Q T S A H S Q R A L Y S W
Cat Felis silvestris
Mouse Mus musculus Q8K561 1137 126412 T227 Y D Q T S A H T Q R A L Y S W
Rat Rattus norvegicus XP_574553 1137 126578 T227 Y D Q T S A H T Q R A L Y S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234949 998 111015 N138 A S W V S A E N L W I L G R Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.1 N.A. 80.5 N.A. 76.3 77.7 N.A. N.A. 52.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.3 N.A. 87.5 N.A. 84.9 85.6 N.A. N.A. 66.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 93.3 N.A. 86.6 86.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 84 0 0 0 0 67 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % G
% His: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % I
% Lys: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 17 0 0 84 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 50 0 0 0 0 0 67 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 67 0 0 0 17 0 % R
% Ser: 0 17 0 0 84 0 0 34 0 0 0 0 0 67 0 % S
% Thr: 0 0 0 67 0 0 0 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 17 0 0 0 0 0 0 17 0 0 0 0 67 % W
% Tyr: 67 0 0 0 0 0 0 0 0 0 0 0 67 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _