KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESSPL
All Species:
4.24
Human Site:
T217
Identified Species:
15.56
UniProt:
Q7RTY5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTY5
NP_899231.2
336
36938
T217
D
K
I
C
A
G
D
T
Q
N
M
K
D
S
C
Chimpanzee
Pan troglodytes
XP_001173227
327
34737
A213
H
L
G
E
P
S
L
A
G
Q
R
L
I
Q
D
Rhesus Macaque
Macaca mulatta
XP_001083326
359
39447
T222
D
K
I
C
A
G
D
T
Q
N
T
K
D
S
C
Dog
Lupus familis
XP_855225
442
47880
I214
D
E
I
C
A
G
D
I
L
N
K
K
D
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q14B25
312
34618
G198
E
Q
L
Y
N
P
I
G
V
F
L
P
D
L
E
Rat
Rattus norvegicus
Q6BEA2
328
35785
I206
S
K
D
A
E
A
D
I
Q
L
K
T
I
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081364
389
42357
K208
D
M
V
C
A
G
Y
K
E
G
R
I
D
A
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38
86.3
47.5
N.A.
58
37.7
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.1
88.5
56.1
N.A.
69.3
50.2
N.A.
N.A.
N.A.
50.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
73.3
N.A.
6.6
20
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
93.3
80
N.A.
33.3
20
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
58
15
0
15
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
58
% C
% Asp:
58
0
15
0
0
0
58
0
0
0
0
0
72
0
29
% D
% Glu:
15
15
0
15
15
0
0
0
15
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
58
0
15
15
15
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
43
0
0
0
15
29
0
0
0
15
29
0
0
% I
% Lys:
0
43
0
0
0
0
0
15
0
0
29
43
0
15
0
% K
% Leu:
0
15
15
0
0
0
15
0
15
15
15
15
0
15
0
% L
% Met:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
43
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
15
0
0
0
0
0
15
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
43
15
0
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% R
% Ser:
15
0
0
0
0
15
0
0
0
0
0
0
0
43
0
% S
% Thr:
0
0
0
0
0
0
0
29
0
0
15
15
0
0
0
% T
% Val:
0
0
15
0
0
0
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
15
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _