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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
28.48
Human Site:
S284
Identified Species:
52.22
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
S284
V
I
S
Q
D
F
D
S
P
C
L
K
N
K
K
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
S284
V
I
S
Q
D
F
D
S
P
C
L
K
N
K
K
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
N234
L
K
N
K
K
H
W
N
S
F
N
T
E
Y
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
S270
V
I
S
Q
D
F
D
S
P
C
L
K
N
K
K
Rat
Rattus norvegicus
Q8K4H4
329
37701
H265
P
C
L
K
N
K
K
H
W
N
S
F
N
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
S282
V
I
S
Q
D
F
D
S
P
W
L
K
N
K
K
Chicken
Gallus gallus
P61798
316
36000
N254
L
K
T
K
K
H
W
N
S
F
T
T
E
Y
F
Frog
Xenopus laevis
Q7T287
347
39626
S275
V
I
S
Q
D
F
D
S
P
C
L
K
N
K
K
Zebra Danio
Brachydanio rerio
P61799
324
36503
N262
L
K
N
K
K
H
W
N
S
F
T
T
D
Y
F
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
S284
V
I
S
Q
D
F
D
S
P
C
L
K
N
K
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
S131
K
T
K
Y
H
W
N
S
F
T
T
P
F
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
S107
K
N
K
K
H
W
N
S
F
T
T
D
Y
F
V
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
S629
V
I
S
Q
D
F
N
S
N
H
L
K
N
K
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
0
N.A.
N.A.
100
6.6
N.A.
93.3
0
100
0
100
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
26.6
N.A.
N.A.
100
26.6
N.A.
93.3
26.6
100
33.3
100
N.A.
20
N.A.
26.6
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
39
0
0
0
0
0
% C
% Asp:
0
0
0
0
54
0
47
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
8
% E
% Phe:
0
0
0
0
0
54
0
0
16
24
0
8
8
16
24
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
16
24
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
24
16
39
24
8
8
0
0
0
0
54
0
54
54
% K
% Leu:
24
0
8
0
0
0
0
0
0
0
54
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
16
0
8
0
24
24
8
8
8
0
62
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
47
0
0
8
0
0
0
% P
% Gln:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
54
0
0
0
0
70
24
0
8
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
0
0
16
31
24
0
8
0
% T
% Val:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
16
24
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
8
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _