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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
13.94
Human Site:
T318
Identified Species:
25.56
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
T318
V
Q
E
A
G
R
V
T
V
R
D
G
M
P
E
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
T318
V
Q
E
A
G
R
V
T
V
R
D
G
M
P
E
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
K268
D
G
M
P
E
L
L
K
L
P
L
R
C
H
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
T304
V
Q
E
A
G
R
V
T
V
K
D
G
T
C
E
Rat
Rattus norvegicus
Q8K4H4
329
37701
L299
V
K
D
G
T
C
E
L
L
K
L
P
L
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
G316
K
Y
C
S
V
A
P
G
P
M
Q
E
I
H
A
Chicken
Gallus gallus
P61798
316
36000
K288
D
Q
A
S
E
L
L
K
L
P
L
R
C
H
L
Frog
Xenopus laevis
Q7T287
347
39626
N309
L
K
T
H
G
K
V
N
V
K
E
R
I
S
D
Zebra Danio
Brachydanio rerio
P61799
324
36503
K296
E
G
A
G
E
L
L
K
L
P
L
R
C
H
V
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
S318
L
E
T
D
G
S
I
S
I
K
E
G
A
T
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
L165
S
E
E
S
A
Q
Y
L
N
T
P
L
K
C
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
K141
R
N
G
E
E
L
L
K
Q
P
L
R
C
H
V
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
T663
I
K
N
H
G
K
A
T
I
K
D
E
D
C
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
6.6
N.A.
0
6.6
20
0
20
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
20
N.A.
N.A.
86.6
40
N.A.
13.3
26.6
66.6
13.3
66.6
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
24
8
8
8
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
31
24
8
% C
% Asp:
16
0
8
8
0
0
0
0
0
0
31
0
8
0
8
% D
% Glu:
8
16
31
8
31
0
8
0
0
0
16
16
0
0
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
8
16
47
0
0
8
0
0
0
31
0
0
0
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
0
39
8
% H
% Ile:
8
0
0
0
0
0
8
0
16
0
0
0
16
0
0
% I
% Lys:
8
24
0
0
0
16
0
31
0
39
0
0
8
0
0
% K
% Leu:
16
0
0
0
0
31
31
16
31
0
39
8
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
16
0
0
% M
% Asn:
0
8
8
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
31
8
8
0
16
0
% P
% Gln:
0
31
0
0
0
8
0
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
0
24
0
0
0
16
0
39
0
8
8
% R
% Ser:
8
0
0
24
0
8
0
8
0
0
0
0
0
8
0
% S
% Thr:
0
0
16
0
8
0
0
31
0
8
0
0
8
8
0
% T
% Val:
31
0
0
0
8
0
31
0
31
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _