KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
8.18
Human Site:
Y110
Identified Species:
15
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
Y110
M
V
N
E
L
Y
P
Y
I
V
E
F
E
E
E
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
Y110
M
V
N
E
L
Y
P
Y
I
V
E
F
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
T62
R
G
P
E
T
K
I
T
D
K
K
C
S
R
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
V96
P
G
Q
V
L
H
M
V
N
G
L
Y
P
Y
I
Rat
Rattus norvegicus
Q8K4H4
329
37701
Y93
L
H
M
V
N
E
L
Y
P
Y
M
V
E
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
D108
D
E
T
G
S
P
D
D
Q
A
P
K
K
K
T
Chicken
Gallus gallus
P61798
316
36000
T82
E
A
E
E
K
I
Q
T
E
K
R
P
C
E
D
Frog
Xenopus laevis
Q7T287
347
39626
E101
P
Y
M
I
E
F
L
E
G
S
T
N
P
R
A
Zebra Danio
Brachydanio rerio
P61799
324
36503
N90
G
Q
S
L
Y
M
V
N
Q
Q
Y
P
Y
S
V
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
S110
L
S
G
S
T
K
R
S
R
E
A
V
S
E
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
C177
L
D
T
L
S
N
G
C
F
G
Q
K
N
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
6.6
N.A.
N.A.
6.6
20
N.A.
0
13.3
0
0
6.6
N.A.
0
N.A.
0
P-Site Similarity:
100
100
20
N.A.
N.A.
20
26.6
N.A.
13.3
20
6.6
6.6
13.3
N.A.
0
N.A.
0
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% C
% Asp:
8
8
0
0
0
0
8
8
8
0
0
0
0
0
16
% D
% Glu:
8
8
8
31
8
8
0
8
8
8
16
0
24
31
24
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
16
0
8
0
% F
% Gly:
8
16
8
8
0
0
8
0
8
16
0
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
0
16
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
16
0
0
0
16
8
16
8
8
0
% K
% Leu:
24
0
0
16
24
0
16
0
0
0
8
0
0
0
0
% L
% Met:
16
0
16
0
0
8
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
16
0
8
8
0
8
8
0
0
8
8
0
0
% N
% Pro:
16
0
8
0
0
8
16
0
8
0
8
16
16
8
0
% P
% Gln:
0
8
8
0
0
0
8
0
16
8
8
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
8
0
8
0
8
0
0
16
0
% R
% Ser:
0
8
8
8
16
0
0
8
0
8
0
0
16
8
0
% S
% Thr:
0
0
16
0
16
0
0
16
0
0
8
0
0
0
16
% T
% Val:
0
16
0
16
0
0
8
8
0
16
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
16
0
24
0
8
8
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _