KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
22.42
Human Site:
Y209
Identified Species:
41.11
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
Y209
V
V
V
I
K
D
K
Y
P
K
A
R
Y
H
W
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
Y209
V
V
V
I
K
D
K
Y
P
K
A
R
Y
H
W
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
W161
Y
H
W
L
V
L
P
W
T
A
I
S
S
L
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
Y195
V
V
V
I
K
D
K
Y
P
K
A
R
H
H
W
Rat
Rattus norvegicus
Q8K4H4
329
37701
L192
A
R
H
H
W
L
V
L
P
W
A
S
I
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
Y207
V
V
V
I
K
D
K
Y
P
K
A
R
N
H
W
Chicken
Gallus gallus
P61798
316
36000
W181
Y
H
W
L
V
L
P
W
D
S
I
S
S
L
K
Frog
Xenopus laevis
Q7T287
347
39626
Y200
I
V
V
I
K
D
K
Y
P
K
A
R
Y
H
W
Zebra Danio
Brachydanio rerio
P61799
324
36503
W189
Y
H
W
L
V
L
P
W
Q
S
I
S
S
L
K
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
Y209
V
V
V
I
K
D
K
Y
P
K
A
R
Y
H
W
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
I58
A
Q
N
H
Y
L
I
I
P
K
I
D
I
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
L34
H
F
L
V
C
P
R
L
K
I
N
N
L
K
A
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
V276
E
N
A
R
F
V
L
V
D
L
S
H
G
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
0
N.A.
N.A.
93.3
13.3
N.A.
93.3
0
93.3
0
100
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
13.3
N.A.
93.3
13.3
100
13.3
100
N.A.
13.3
N.A.
20
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
0
0
8
54
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
47
0
0
16
0
0
8
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
8
24
8
16
0
0
0
0
0
0
0
8
8
47
0
% H
% Ile:
8
0
0
47
0
0
8
8
0
8
31
0
16
0
0
% I
% Lys:
0
0
0
0
47
0
47
0
8
54
0
0
0
8
31
% K
% Leu:
0
0
8
24
0
39
8
16
0
8
0
0
8
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
8
24
0
62
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
8
0
0
0
0
47
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
16
8
31
24
16
16
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
39
47
47
8
24
8
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
24
0
8
0
0
24
0
8
0
0
0
0
47
% W
% Tyr:
24
0
0
0
8
0
0
47
0
0
0
0
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _