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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
24.24
Human Site:
Y264
Identified Species:
44.44
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
Y264
K
L
R
F
R
L
G
Y
H
A
I
P
S
M
S
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
Y264
K
L
R
F
R
L
G
Y
H
A
I
P
S
M
S
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
H214
I
P
S
M
S
H
V
H
L
H
V
I
S
Q
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
Y250
K
L
R
F
R
L
G
Y
H
A
I
P
S
M
S
Rat
Rattus norvegicus
Q8K4H4
329
37701
H245
H
A
I
P
S
M
S
H
V
H
L
H
V
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
Y262
R
L
Q
F
R
M
G
Y
H
A
I
P
S
M
S
Chicken
Gallus gallus
P61798
316
36000
H234
I
P
S
M
S
Q
L
H
L
H
V
I
S
Q
D
Frog
Xenopus laevis
Q7T287
347
39626
Y255
C
A
P
F
R
F
G
Y
H
A
I
P
S
M
S
Zebra Danio
Brachydanio rerio
P61799
324
36503
H242
I
P
S
M
S
H
V
H
L
H
V
I
S
Q
D
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
Y264
T
P
R
F
R
S
G
Y
H
A
I
P
S
M
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
L111
P
S
M
H
R
L
H
L
H
V
I
S
T
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
L87
P
S
M
S
H
L
H
L
H
A
I
S
R
D
F
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
Y609
S
M
V
F
R
L
G
Y
H
S
V
P
S
M
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
6.6
N.A.
80
6.6
73.3
6.6
80
N.A.
26.6
N.A.
26.6
P-Site Similarity:
100
100
20
N.A.
N.A.
100
33.3
N.A.
100
20
73.3
20
80
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
54
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
24
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
54
0
8
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
8
8
16
16
31
70
31
0
8
0
0
0
% H
% Ile:
24
0
8
0
0
0
0
0
0
0
62
24
0
8
0
% I
% Lys:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
31
0
0
0
47
8
16
24
0
8
0
0
0
0
% L
% Met:
0
8
16
24
0
16
0
0
0
0
0
0
0
54
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
31
8
8
0
0
0
0
0
0
0
54
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
0
0
0
0
24
0
% Q
% Arg:
8
0
31
0
62
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
8
16
24
8
31
8
8
0
0
8
0
16
77
0
54
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
0
0
16
0
8
8
31
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _