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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APTX
All Species:
22.12
Human Site:
Y300
Identified Species:
40.56
UniProt:
Q7Z2E3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2E3
NP_060162.1
356
40740
Y300
W
N
S
F
N
T
E
Y
F
L
E
S
Q
A
V
Chimpanzee
Pan troglodytes
XP_001158355
356
40779
Y300
W
N
S
F
N
T
E
Y
F
L
E
S
Q
A
V
Rhesus Macaque
Macaca mulatta
XP_001090958
296
34012
M250
E
S
Q
A
V
I
E
M
V
Q
E
A
G
R
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQC5
342
38704
Y286
W
N
S
F
N
T
E
Y
F
L
E
S
Q
A
V
Rat
Rattus norvegicus
Q8K4H4
329
37701
I281
F
L
E
S
Q
A
V
I
K
M
V
Q
E
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506988
408
45957
Y298
W
N
S
F
N
T
K
Y
F
L
E
S
Q
A
I
Chicken
Gallus gallus
P61798
316
36000
M270
N
S
E
E
V
I
E
M
V
R
S
K
G
K
V
Frog
Xenopus laevis
Q7T287
347
39626
Y291
W
N
S
F
T
T
D
Y
F
L
E
S
Q
A
V
Zebra Danio
Brachydanio rerio
P61799
324
36503
M278
E
S
Q
D
V
I
S
M
L
E
H
D
G
K
V
Tiger Blowfish
Takifugu rubipres
P61800
356
40172
Y300
W
N
S
F
T
T
D
Y
F
I
E
S
Q
A
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392143
194
22668
L147
S
T
D
I
C
N
Q
L
R
E
K
G
E
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797394
169
19599
L123
S
M
E
L
I
A
E
L
E
E
N
G
C
V
D
Poplar Tree
Populus trichocarpa
XP_002323598
718
79266
F645
W
N
S
F
N
T
A
F
F
R
D
S
V
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
78.6
N.A.
N.A.
82
78.3
N.A.
52.4
48
57
54.7
55.6
N.A.
24.4
N.A.
26.9
Protein Similarity:
100
99.7
79.2
N.A.
N.A.
87.3
83.1
N.A.
63.9
60.6
73.3
69
71.9
N.A.
35.9
N.A.
36.2
P-Site Identity:
100
100
20
N.A.
N.A.
100
6.6
N.A.
86.6
13.3
86.6
6.6
80
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
26.6
N.A.
100
20
93.3
13.3
93.3
N.A.
20
N.A.
6.6
Percent
Protein Identity:
23.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
16
8
0
0
0
0
8
0
54
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
0
0
16
0
0
0
8
8
0
8
8
% D
% Glu:
16
0
24
8
0
0
47
0
8
24
54
0
16
0
0
% E
% Phe:
8
0
0
54
0
0
0
8
54
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
16
24
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
8
24
0
8
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
8
8
0
16
8
% K
% Leu:
0
8
0
8
0
0
0
16
8
39
0
0
0
8
0
% L
% Met:
0
8
0
0
0
0
0
24
0
8
0
0
0
0
0
% M
% Asn:
8
54
0
0
39
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
8
0
8
0
0
8
0
8
47
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
16
0
0
0
8
0
% R
% Ser:
16
24
54
8
0
0
8
0
0
0
8
54
0
0
0
% S
% Thr:
0
8
0
0
16
54
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
24
0
8
0
16
0
8
0
8
8
70
% V
% Trp:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _