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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC36A1 All Species: 31.52
Human Site: T423 Identified Species: 63.03
UniProt: Q7Z2H8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z2H8 NP_510968.2 476 53076 T423 P P L L E V T T F Y S E G M S
Chimpanzee Pan troglodytes XP_001168164 476 53110 T423 P P L L E V T T F Y S E G M S
Rhesus Macaque Macaca mulatta XP_001110090 476 53047 T423 P P L L E V T T F Y S E G M S
Dog Lupus familis XP_546291 507 55973 T454 P P L L E I T T Y Y S E G M S
Cat Felis silvestris
Mouse Mus musculus Q8K4D3 475 52447 T422 P P L L E V V T Y Y G E G I S
Rat Rattus norvegicus Q924A5 475 52550 T422 P P L L E V T T Y Y G E G I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512780 553 62169 T488 P P L V E I L T F Y K E N L C
Chicken Gallus gallus XP_001233582 482 53065 A430 F P P L L E I A T Y Y T E G M
Frog Xenopus laevis Q4KL91 522 58726 T459 P P L V E I I T Y H K E N L S
Zebra Danio Brachydanio rerio Q6DEL1 465 50660 C412 I F V F P G L C L I Q A K L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34479 460 51320 T408 P P F F E M I T F W T D W K G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50944 713 80007 V652 N L D K F V S V I G S L A C I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.5 87.9 N.A. 85.9 85.7 N.A. 49.5 54.5 49.6 21.4 N.A. N.A. N.A. 27.9 N.A.
Protein Similarity: 100 99.7 99.5 91.3 N.A. 92.8 93.2 N.A. 63.6 67.4 66.4 43.2 N.A. N.A. N.A. 48.5 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. 53.3 20 46.6 6.6 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 73.3 20 80 20 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 9 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 75 9 0 0 0 0 0 67 9 0 0 % E
% Phe: 9 9 9 17 9 0 0 0 42 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 9 17 0 50 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 25 25 0 9 9 0 0 0 17 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 17 0 9 9 0 % K
% Leu: 0 9 67 59 9 0 17 0 9 0 0 9 0 25 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 34 9 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 75 84 9 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 42 0 0 0 67 % S
% Thr: 0 0 0 0 0 0 42 75 9 0 9 9 0 0 0 % T
% Val: 0 0 9 17 0 50 9 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 34 67 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _