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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3HAV1 All Species: 6.67
Human Site: S724 Identified Species: 18.33
UniProt: Q7Z2W4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z2W4 NP_064504.2 902 101431 S724 Q E D F C F L S S K K Y K L S
Chimpanzee Pan troglodytes XP_527904 902 101438 S724 Q E D F C F L S S K K Y K L S
Rhesus Macaque Macaca mulatta XP_001108942 701 78961 Q527 T L P F Y F V Q K I E R V Q N
Dog Lupus familis XP_539894 2910 313916 N768 M K N F K I E N I K K I K N T
Cat Felis silvestris
Mouse Mus musculus Q3UPF5 946 106669 Y749 F H A G S Q N Y E L S F Q G M
Rat Rattus norvegicus Q8K3Y6 776 86752 S602 L Y K G C Q Q S H C D R S H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012956 713 81639 I539 I S S E Y Q E I K K Q F E Q T
Frog Xenopus laevis NP_001088385 503 58277 S329 V K R L S T P S S A S K P P H
Zebra Danio Brachydanio rerio XP_695578 663 75552 Q489 T Y K I V S L Q K T C K E Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 21.1 21.2 N.A. 50.3 36.2 N.A. N.A. 36.4 23.9 26.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.5 36.7 25.5 N.A. 64.1 50.8 N.A. N.A. 51.1 34.1 43.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 26.6 N.A. 0 13.3 N.A. N.A. 6.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 53.3 N.A. 13.3 13.3 N.A. N.A. 33.3 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % A
% Cys: 0 0 0 0 34 0 0 0 0 12 12 0 0 0 0 % C
% Asp: 0 0 23 0 0 0 0 0 0 0 12 0 0 0 0 % D
% Glu: 0 23 0 12 0 0 23 0 12 0 12 0 23 0 12 % E
% Phe: 12 0 0 45 0 34 0 0 0 0 0 23 0 0 12 % F
% Gly: 0 0 0 23 0 0 0 0 0 0 0 0 0 12 0 % G
% His: 0 12 0 0 0 0 0 0 12 0 0 0 0 12 12 % H
% Ile: 12 0 0 12 0 12 0 12 12 12 0 12 0 0 0 % I
% Lys: 0 23 23 0 12 0 0 0 34 45 34 23 34 0 0 % K
% Leu: 12 12 0 12 0 0 34 0 0 12 0 0 0 23 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 12 0 0 0 12 12 0 0 0 0 0 12 12 % N
% Pro: 0 0 12 0 0 0 12 0 0 0 0 0 12 12 0 % P
% Gln: 23 0 0 0 0 34 12 23 0 0 12 0 12 23 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 23 0 0 0 % R
% Ser: 0 12 12 0 23 12 0 45 34 0 23 0 12 0 23 % S
% Thr: 23 0 0 0 0 12 0 0 0 12 0 0 0 0 23 % T
% Val: 12 0 0 0 12 0 12 0 0 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 0 23 0 0 12 0 0 0 23 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _