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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPM8
All Species:
19.7
Human Site:
T600
Identified Species:
48.15
UniProt:
Q7Z2W7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2W7
NP_076985.4
1104
127685
T600
G
A
S
K
L
L
K
T
L
A
K
V
K
N
D
Chimpanzee
Pan troglodytes
XP_001151868
1449
165207
E641
A
C
S
K
I
L
K
E
L
S
K
E
E
E
D
Rhesus Macaque
Macaca mulatta
XP_001093334
1165
131044
K608
R
R
N
R
C
W
S
K
T
T
C
L
H
L
A
Dog
Lupus familis
XP_540789
1174
132628
L579
A
L
A
A
C
K
I
L
R
E
M
S
H
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4D5
1104
127691
T600
G
A
S
K
L
L
K
T
L
A
K
V
K
N
D
Rat
Rattus norvegicus
Q8R455
1104
127610
T600
G
A
S
K
L
L
K
T
L
A
K
V
K
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510600
942
108897
V499
S
N
C
L
E
L
A
V
E
A
R
D
Q
Q
F
Chicken
Gallus gallus
NP_001007083
1095
126780
S591
G
A
S
K
L
L
K
S
M
A
K
V
K
N
D
Frog
Xenopus laevis
NP_001155066
1139
131628
S636
G
A
S
K
L
L
K
S
L
A
K
V
K
N
D
Zebra Danio
Brachydanio rerio
NP_001121711
1160
131872
T581
Y
S
L
L
V
R
K
T
C
C
W
S
K
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.6
33.7
33.4
N.A.
93.7
93.7
N.A.
76.9
80.7
74
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.1
52
52.5
N.A.
97.3
97.2
N.A.
81.4
90.3
84.9
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
0
0
N.A.
100
100
N.A.
13.3
86.6
93.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
20
13.3
N.A.
100
100
N.A.
26.6
100
100
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
50
10
10
0
0
10
0
0
60
0
0
0
10
10
% A
% Cys:
0
10
10
0
20
0
0
0
10
10
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
60
% D
% Glu:
0
0
0
0
10
0
0
10
10
10
0
10
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
60
0
10
70
10
0
0
60
0
60
0
0
% K
% Leu:
0
10
10
20
50
70
0
10
50
0
0
10
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
10
0
10
0
10
0
0
10
0
10
0
0
0
0
% R
% Ser:
10
10
60
0
0
0
10
20
0
10
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
10
10
0
0
0
0
10
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _