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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL21
All Species:
30
Human Site:
S166
Identified Species:
55
UniProt:
Q7Z2W9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2W9
NP_852615.1
205
22815
S166
T
V
I
E
K
T
E
S
W
P
R
I
I
M
R
Chimpanzee
Pan troglodytes
XP_001173868
209
23109
S170
T
V
I
E
K
T
E
S
W
P
R
I
I
M
R
Rhesus Macaque
Macaca mulatta
XP_001101761
209
23115
S170
T
V
I
E
K
T
E
S
W
P
R
I
I
M
R
Dog
Lupus familis
XP_533207
209
22861
S170
T
V
I
E
K
T
E
S
W
P
K
I
N
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1N9
209
23348
S170
T
V
I
E
K
T
E
S
W
P
K
I
N
M
K
Rat
Rattus norvegicus
NP_001101037
209
23372
S170
T
V
I
E
K
T
E
S
W
P
K
I
N
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517350
102
11171
H70
G
R
L
F
A
V
V
H
F
A
S
Q
Q
W
K
Chicken
Gallus gallus
XP_420932
189
21328
S150
T
V
I
E
K
T
V
S
W
P
K
I
N
M
R
Frog
Xenopus laevis
NP_001089790
201
22524
S162
T
V
I
E
K
T
E
S
Y
P
K
I
S
M
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121076
198
23182
N165
R
K
Q
Y
K
R
L
N
F
Y
R
I
H
R
T
Nematode Worm
Caenorhab. elegans
NP_001022585
171
19051
V139
T
N
P
E
L
H
Y
V
H
L
N
H
H
Q
T
Sea Urchin
Strong. purpuratus
XP_001188369
142
15820
H110
T
I
S
E
K
K
V
H
F
R
F
K
K
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9A0
270
30889
I214
A
L
D
E
K
V
L
I
F
K
K
K
R
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
91.3
77.9
N.A.
79.9
79.9
N.A.
33.6
64.8
58
N.A.
N.A.
N.A.
32.6
33.6
40.9
Protein Similarity:
100
97.6
94.2
85.6
N.A.
86.5
85.1
N.A.
40.9
77.5
71.2
N.A.
N.A.
N.A.
54.1
48.2
49.2
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
0
80
80
N.A.
N.A.
N.A.
20
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
86.6
93.3
N.A.
N.A.
N.A.
33.3
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
85
0
0
54
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
31
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
16
8
0
0
8
16
0
0
% H
% Ile:
0
8
62
0
0
0
0
8
0
0
0
70
24
0
0
% I
% Lys:
0
8
0
0
85
8
0
0
0
8
47
16
8
0
47
% K
% Leu:
0
8
8
0
8
0
16
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
8
0
31
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
62
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
8
8
8
0
% Q
% Arg:
8
8
0
0
0
8
0
0
0
8
31
0
8
24
39
% R
% Ser:
0
0
8
0
0
0
0
62
0
0
8
0
8
0
0
% S
% Thr:
77
0
0
0
0
62
0
0
0
0
0
0
0
0
16
% T
% Val:
0
62
0
0
0
16
24
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
54
0
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
8
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _