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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL21
All Species:
16.36
Human Site:
S18
Identified Species:
30
UniProt:
Q7Z2W9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2W9
NP_852615.1
205
22815
S18
G
R
L
A
S
A
C
S
H
S
I
L
R
P
S
Chimpanzee
Pan troglodytes
XP_001173868
209
23109
S22
G
R
L
A
S
A
C
S
H
S
I
L
R
P
S
Rhesus Macaque
Macaca mulatta
XP_001101761
209
23115
S22
G
R
L
V
S
A
G
S
R
S
I
L
R
P
S
Dog
Lupus familis
XP_533207
209
22861
S22
R
R
L
L
C
A
C
S
R
R
G
P
R
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1N9
209
23348
S22
G
R
L
V
S
V
C
S
R
S
I
L
A
S
Q
Rat
Rattus norvegicus
NP_001101037
209
23372
R22
G
R
L
V
S
V
C
R
R
S
I
L
A
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517350
102
11171
Chicken
Gallus gallus
XP_420932
189
21328
S18
A
A
A
F
L
F
S
S
V
V
R
L
Q
S
S
Frog
Xenopus laevis
NP_001089790
201
22524
A24
E
G
V
R
C
A
A
A
V
T
L
F
R
P
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121076
198
23182
R28
E
I
R
V
D
G
Y
R
T
R
Y
K
L
P
W
Nematode Worm
Caenorhab. elegans
NP_001022585
171
19051
L11
S
R
C
A
S
L
L
L
S
S
S
Q
S
I
L
Sea Urchin
Strong. purpuratus
XP_001188369
142
15820
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9A0
270
30889
S40
E
F
S
G
T
S
I
S
H
G
T
V
I
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
91.3
77.9
N.A.
79.9
79.9
N.A.
33.6
64.8
58
N.A.
N.A.
N.A.
32.6
33.6
40.9
Protein Similarity:
100
97.6
94.2
85.6
N.A.
86.5
85.1
N.A.
40.9
77.5
71.2
N.A.
N.A.
N.A.
54.1
48.2
49.2
P-Site Identity:
100
100
80
40
N.A.
60
53.3
N.A.
0
20
20
N.A.
N.A.
N.A.
6.6
26.6
0
P-Site Similarity:
100
100
80
46.6
N.A.
60
53.3
N.A.
0
26.6
46.6
N.A.
N.A.
N.A.
6.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
24
0
39
8
8
0
0
0
0
16
8
8
% A
% Cys:
0
0
8
0
16
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
8
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
39
8
0
8
0
8
8
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
39
0
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
47
8
8
8
8
8
0
0
8
47
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
47
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
16
% Q
% Arg:
8
54
8
8
0
0
0
16
31
16
8
0
39
0
0
% R
% Ser:
8
0
8
0
47
8
8
54
8
47
8
0
8
24
31
% S
% Thr:
0
0
0
0
8
0
0
0
8
8
8
0
0
0
0
% T
% Val:
0
0
8
31
0
16
0
0
16
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _