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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETX All Species: 4.24
Human Site: S642 Identified Species: 13.33
UniProt: Q7Z333 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z333 NP_055861.3 2677 302979 S642 M H C L E A S S P T F S K E P
Chimpanzee Pan troglodytes XP_001168250 2668 301587 S642 T H C L E A S S P T F S K E P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537811 2693 305788 F645 L E N S S P T F P K E S I K A
Cat Felis silvestris
Mouse Mus musculus A2AKX3 2646 297571 C639 N I Y C L E N C S P V S S K E
Rat Rattus norvegicus XP_342401 2647 297288 G637 K K D I H S L G N C S P I P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519791 1477 162982
Chicken Gallus gallus XP_415453 2111 238225 R213 F E S P D I Y R S S V I E K G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690945 2046 230544 D148 R V L Y K L Q D W Q Q T L S W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 80.3 N.A. 72 71.5 N.A. 22 44.8 N.A. 28.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 N.A. 88.2 N.A. 82.6 81.8 N.A. 34.4 57.2 N.A. 45.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 N.A. 13.3 N.A. 6.6 0 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 33.3 N.A. 20 13.3 N.A. 0 26.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 25 13 0 0 0 13 0 13 0 0 0 0 0 % C
% Asp: 0 0 13 0 13 0 0 13 0 0 0 0 0 0 0 % D
% Glu: 0 25 0 0 25 13 0 0 0 0 13 0 13 25 13 % E
% Phe: 13 0 0 0 0 0 0 13 0 0 25 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 13 % G
% His: 0 25 0 0 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 13 0 13 0 0 0 0 0 13 25 0 0 % I
% Lys: 13 13 0 0 13 0 0 0 0 13 0 0 25 38 0 % K
% Leu: 13 0 13 25 13 13 13 0 0 0 0 0 13 0 0 % L
% Met: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 13 0 0 0 13 0 13 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 0 13 0 0 38 13 0 13 0 13 25 % P
% Gln: 0 0 0 0 0 0 13 0 0 13 13 0 0 0 0 % Q
% Arg: 13 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 13 13 13 25 25 25 13 13 50 13 13 13 % S
% Thr: 13 0 0 0 0 0 13 0 0 25 0 13 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 0 0 25 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 13 % W
% Tyr: 0 0 13 13 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _