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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEGR1 All Species: 31.82
Human Site: T117 Identified Species: 70
UniProt: Q7Z3B1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3B1 NP_776169.2 354 38719 T117 V T D D G P Y T C S V Q T Q H
Chimpanzee Pan troglodytes XP_001167037 355 38819 T117 V T D D G P Y T C S V Q T Q H
Rhesus Macaque Macaca mulatta XP_001099596 354 38717 T117 V T D D G P Y T C S V Q T Q H
Dog Lupus familis XP_855525 457 49213 I131 T G K P E P S I S W R H I S P
Cat Felis silvestris
Mouse Mus musculus Q80Z24 348 37882 T111 V T D D G P Y T C S V Q T Q H
Rat Rattus norvegicus Q9Z0J8 348 37840 T111 V T D D G P Y T C S V Q T Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509074 360 39089 T117 V T D D G P Y T C S V Q T Q H
Chicken Gallus gallus Q9W6V2 352 37926 T115 V T D D G P Y T C S V Q T Q H
Frog Xenopus laevis NP_001086181 337 37542 Y109 D V S D E G P Y I C S V Q T N
Zebra Danio Brachydanio rerio NP_001003851 346 37540 T118 V T D E G V Y T C S I Q S E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24372 359 39921 Q114 D A G T Y T C Q V V I S T V H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 98.5 61.2 N.A. 94 94.3 N.A. 84.7 81.9 50.5 62.1 N.A. 26.1 N.A. N.A. N.A.
Protein Similarity: 100 98.3 100 65.2 N.A. 96 96.3 N.A. 89.7 89.5 66.6 78.5 N.A. 42.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 100 100 6.6 60 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 100 100 13.3 86.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 73 10 0 0 0 0 0 % C
% Asp: 19 0 73 73 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 19 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 73 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 73 % H
% Ile: 0 0 0 0 0 0 0 10 10 0 19 0 10 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 10 0 73 10 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 73 10 64 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % R
% Ser: 0 0 10 0 0 0 10 0 10 73 10 10 10 10 0 % S
% Thr: 10 73 0 10 0 10 0 73 0 0 0 0 73 10 0 % T
% Val: 73 10 0 0 0 10 0 0 10 10 64 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 73 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _