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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEGR1
All Species:
26.97
Human Site:
T283
Identified Species:
59.33
UniProt:
Q7Z3B1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3B1
NP_776169.2
354
38719
T283
F
S
T
R
S
I
L
T
V
T
N
V
T
Q
E
Chimpanzee
Pan troglodytes
XP_001167037
355
38819
T284
F
S
T
R
S
I
L
T
V
T
N
V
T
Q
E
Rhesus Macaque
Macaca mulatta
XP_001099596
354
38717
T283
F
S
T
R
S
I
L
T
V
T
N
V
T
Q
E
Dog
Lupus familis
XP_855525
457
49213
G380
R
P
T
T
E
S
S
G
S
K
R
I
V
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z24
348
37882
T277
F
S
T
R
S
I
L
T
V
T
N
V
T
Q
E
Rat
Rattus norvegicus
Q9Z0J8
348
37840
T277
F
S
T
R
S
I
L
T
V
T
N
V
T
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509074
360
39089
T289
Y
G
S
R
S
I
L
T
V
S
N
V
T
Q
E
Chicken
Gallus gallus
Q9W6V2
352
37926
T281
Y
S
T
R
S
L
L
T
V
T
N
V
T
E
E
Frog
Xenopus laevis
NP_001086181
337
37542
R267
S
A
Q
G
L
E
I
R
N
T
G
S
R
S
V
Zebra Danio
Brachydanio rerio
NP_001003851
346
37540
L276
Q
G
I
V
I
N
N
L
S
S
R
S
V
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24372
359
39921
R289
E
Y
T
D
S
T
L
R
V
I
T
V
E
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
98.5
61.2
N.A.
94
94.3
N.A.
84.7
81.9
50.5
62.1
N.A.
26.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
100
65.2
N.A.
96
96.3
N.A.
89.7
89.5
66.6
78.5
N.A.
42.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
73.3
80
6.6
0
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
93.3
100
20
6.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
10
0
0
0
0
0
0
10
10
64
% E
% Phe:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
10
0
0
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
55
10
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
10
73
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
10
0
64
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
55
0
% Q
% Arg:
10
0
0
64
0
0
0
19
0
0
19
0
10
0
10
% R
% Ser:
10
55
10
0
73
10
10
0
19
19
0
19
0
10
0
% S
% Thr:
0
0
73
10
0
10
0
64
0
64
10
0
64
0
10
% T
% Val:
0
0
0
10
0
0
0
0
73
0
0
73
19
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _