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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP54
All Species:
30.61
Human Site:
Y375
Identified Species:
56.11
UniProt:
Q7Z3B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3B4
NP_059122.2
507
55435
Y375
S
V
A
K
I
A
Q
Y
K
R
K
L
M
D
L
Chimpanzee
Pan troglodytes
XP_001150700
459
50757
T338
L
M
D
L
S
H
R
T
L
Q
V
L
I
K
Q
Rhesus Macaque
Macaca mulatta
XP_001096676
459
50756
T338
L
M
D
L
S
H
R
T
L
Q
V
L
I
K
Q
Dog
Lupus familis
XP_544935
460
48982
T339
L
G
I
T
L
S
M
T
R
T
E
L
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTS4
510
55713
Y378
T
M
A
K
I
A
Q
Y
K
R
K
L
M
E
L
Rat
Rattus norvegicus
P70582
510
55726
Y378
T
M
A
K
I
A
Q
Y
K
R
K
L
M
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509878
1198
131683
Y681
T
M
A
K
I
A
Q
Y
K
R
K
L
M
D
L
Chicken
Gallus gallus
XP_420594
503
55210
Y371
T
M
A
K
I
A
Q
Y
K
R
K
L
M
A
L
Frog
Xenopus laevis
NP_001083202
502
55374
Y370
T
M
A
K
I
G
Q
Y
K
R
K
L
M
E
L
Zebra Danio
Brachydanio rerio
XP_002665869
526
55848
Y394
T
A
A
K
I
T
Q
Y
K
R
K
L
M
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6B9
610
64378
H484
A
T
A
K
I
L
E
H
K
R
K
L
A
E
L
Honey Bee
Apis mellifera
XP_394448
621
67296
H492
I
Q
A
R
L
K
E
H
R
R
T
L
L
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786754
536
58274
N411
L
Q
A
R
I
A
E
N
K
R
R
H
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.1
76.1
N.A.
95.4
95.2
N.A.
39.3
88.1
80.4
51.7
N.A.
37.5
38
N.A.
50
Protein Similarity:
100
90.3
90.3
78.1
N.A.
97.8
98
N.A.
40.6
93.2
89.9
64
N.A.
51.6
54.5
N.A.
65.8
P-Site Identity:
100
6.6
6.6
6.6
N.A.
80
86.6
N.A.
86.6
80
73.3
80
N.A.
53.3
26.6
N.A.
40
P-Site Similarity:
100
33.3
33.3
33.3
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
80
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
77
0
0
47
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
0
0
0
0
0
0
31
0
% D
% Glu:
0
0
0
0
0
0
24
0
0
0
8
0
0
39
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
16
0
16
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
70
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
0
0
0
62
0
8
0
0
70
0
62
0
0
16
0
% K
% Leu:
31
0
0
16
16
8
0
0
16
0
0
93
16
0
77
% L
% Met:
0
54
0
0
0
0
8
0
0
0
0
0
54
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
16
0
0
0
0
54
0
0
16
0
0
0
0
16
% Q
% Arg:
0
0
0
16
0
0
16
0
16
77
8
0
0
0
0
% R
% Ser:
8
0
0
0
16
8
0
0
0
0
0
0
8
0
0
% S
% Thr:
47
8
0
8
0
8
0
24
0
8
8
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _