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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYSMD3
All Species:
25.76
Human Site:
S252
Identified Species:
51.52
UniProt:
Q7Z3D4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3D4
NP_938014.1
306
34538
S252
K
V
D
V
S
H
H
S
T
V
D
S
S
H
L
Chimpanzee
Pan troglodytes
XP_517659
461
51917
S407
K
V
D
V
S
H
H
S
T
V
D
S
S
H
L
Rhesus Macaque
Macaca mulatta
XP_001086208
415
46471
S361
K
V
D
V
S
H
H
S
T
V
D
S
S
H
L
Dog
Lupus familis
XP_546030
305
34309
S252
K
V
D
V
S
H
H
S
T
M
D
S
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LE3
305
34239
S251
K
V
D
V
S
H
H
S
T
V
G
S
S
H
L
Rat
Rattus norvegicus
Q5M836
300
33683
V247
E
I
L
A
K
V
D
V
S
H
H
S
T
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510165
381
42155
S327
K
V
D
V
S
H
H
S
T
V
E
S
S
Q
S
Chicken
Gallus gallus
Q5ZKK0
300
33397
S247
K
A
D
V
S
H
H
S
T
M
E
S
A
H
S
Frog
Xenopus laevis
Q6DCC7
289
32035
D236
V
Y
F
K
T
Q
G
D
S
E
G
T
F
S
I
Zebra Danio
Brachydanio rerio
Q6IQA2
305
34045
A250
Y
Y
E
V
L
M
K
A
D
V
S
H
H
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122475
209
23442
G156
E
E
S
H
G
V
T
G
F
H
F
V
T
A
R
Sea Urchin
Strong. purpuratus
XP_001177760
290
32783
F237
S
V
L
K
E
T
R
F
R
P
L
H
F
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.9
71.8
90.5
N.A.
80
79
N.A.
56.1
63.4
35.6
48.3
N.A.
N.A.
N.A.
21.5
25.8
Protein Similarity:
100
66.3
73
94.1
N.A.
88.2
87.2
N.A.
64.8
75.4
54.2
65.6
N.A.
N.A.
N.A.
39.8
46.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
80
66.6
0
13.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
86.6
86.6
26.6
26.6
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
9
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
59
0
0
0
9
9
9
0
34
0
0
0
9
% D
% Glu:
17
9
9
0
9
0
0
0
0
9
17
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
9
9
0
9
0
17
0
0
% F
% Gly:
0
0
0
0
9
0
9
9
0
0
17
0
0
0
0
% G
% His:
0
0
0
9
0
59
59
0
0
17
9
17
9
50
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
59
0
0
17
9
0
9
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
17
0
9
0
0
0
0
0
9
0
0
0
42
% L
% Met:
0
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
9
% R
% Ser:
9
0
9
0
59
0
0
59
17
0
9
67
50
9
17
% S
% Thr:
0
0
0
0
9
9
9
0
59
0
0
9
17
9
9
% T
% Val:
9
59
0
67
0
17
0
9
0
50
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _