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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRICKLE2 All Species: 26.36
Human Site: S307 Identified Species: 58
UniProt: Q7Z3G6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3G6 NP_942559.1 844 95615 S307 K Q G Q I F C S R A C S A G E
Chimpanzee Pan troglodytes XP_520681 844 95614 S307 K Q G Q I F C S R A C S A G E
Rhesus Macaque Macaca mulatta XP_001089576 1098 122550 S561 K Q G Q I F C S R A C S A G E
Dog Lupus familis XP_541815 945 107213 S407 K Q G Q I F C S R A C S A G E
Cat Felis silvestris
Mouse Mus musculus Q80Y24 845 95821 S307 K Q G Q I F C S R A C S A G E
Rat Rattus norvegicus Q71QF9 831 94152 Q297 G C P F L P K Q G Q I Y C S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508261 882 99961 S347 K Q G Q I F C S R A C S A G E
Chicken Gallus gallus XP_001234704 864 97886 G330 R P F L P K Q G Q I F C S R A
Frog Xenopus laevis Q90WV2 832 94675 G298 C P F L P K K G R I Y C S K A
Zebra Danio Brachydanio rerio NP_001071251 869 98168 S303 K Q G L I Y C S R L C S Q G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194491 836 95332 V303 Y F Y R E G K V Y C G R H H A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 76.6 85.6 N.A. 95 50.3 N.A. 88.3 84 48.3 55 N.A. N.A. N.A. N.A. 40.6
Protein Similarity: 100 100 76.8 87.9 N.A. 97.7 64.2 N.A. 92.2 90.1 63.3 69.1 N.A. N.A. N.A. N.A. 54.9
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 0 6.6 66.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 20 13.3 80 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 55 0 0 55 0 28 % A
% Cys: 10 10 0 0 0 0 64 0 0 10 64 19 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 55 % E
% Phe: 0 10 19 10 0 55 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 64 0 0 10 0 19 10 0 10 0 0 64 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 64 0 0 0 0 19 10 0 0 0 0 % I
% Lys: 64 0 0 0 0 19 28 0 0 0 0 0 0 10 10 % K
% Leu: 0 0 0 28 10 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 10 0 19 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 64 0 55 0 0 10 10 10 10 0 0 10 0 0 % Q
% Arg: 10 0 0 10 0 0 0 0 73 0 0 10 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 64 0 0 0 64 19 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 10 0 0 10 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _