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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE2
All Species:
10.91
Human Site:
Y503
Identified Species:
24
UniProt:
Q7Z3G6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3G6
NP_942559.1
844
95615
Y503
G
S
I
Q
V
P
K
Y
E
E
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_520681
844
95614
Y503
G
S
I
Q
V
P
K
Y
E
E
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001089576
1098
122550
Y757
G
S
I
Q
V
P
K
Y
E
E
E
E
E
E
E
Dog
Lupus familis
XP_541815
945
107213
E604
N
I
P
V
P
K
Y
E
E
E
E
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
E504
S
I
P
V
P
K
Y
E
E
E
E
E
E
E
E
Rat
Rattus norvegicus
Q71QF9
831
94152
P491
A
Y
G
S
H
P
G
P
A
S
S
R
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
K541
R
G
S
I
K
V
P
K
Y
D
E
E
E
G
E
Chicken
Gallus gallus
XP_001234704
864
97886
K523
P
E
T
R
G
S
L
K
V
P
K
Y
E
E
E
Frog
Xenopus laevis
Q90WV2
832
94675
S491
G
S
H
P
G
P
A
S
S
R
K
L
Q
E
L
Zebra Danio
Brachydanio rerio
NP_001071251
869
98168
K519
R
N
S
G
F
L
D
K
R
S
I
S
V
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
R496
R
S
K
D
M
S
R
R
S
L
P
D
L
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.6
85.6
N.A.
95
50.3
N.A.
88.3
84
48.3
55
N.A.
N.A.
N.A.
N.A.
40.6
Protein Similarity:
100
100
76.8
87.9
N.A.
97.7
64.2
N.A.
92.2
90.1
63.3
69.1
N.A.
N.A.
N.A.
N.A.
54.9
P-Site Identity:
100
100
100
46.6
N.A.
46.6
6.6
N.A.
26.6
20
26.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
13.3
N.A.
33.3
33.3
40
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
10
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
19
46
46
55
55
64
64
64
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
10
10
10
19
0
10
0
0
0
0
0
0
10
10
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
28
10
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
10
19
28
28
0
0
19
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
10
0
10
10
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
19
10
19
46
10
10
0
10
10
0
0
0
0
% P
% Gln:
0
0
0
28
0
0
0
0
0
0
0
0
10
10
10
% Q
% Arg:
28
0
0
10
0
0
10
10
10
10
0
10
10
10
0
% R
% Ser:
10
46
19
10
0
19
0
10
19
19
10
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
19
28
10
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
19
28
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _