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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE2
All Species:
22.73
Human Site:
Y614
Identified Species:
50
UniProt:
Q7Z3G6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3G6
NP_942559.1
844
95615
Y614
S
L
L
S
A
Q
Q
Y
Q
E
M
E
G
N
L
Chimpanzee
Pan troglodytes
XP_520681
844
95614
Y614
S
L
L
S
A
Q
Q
Y
Q
E
M
E
G
N
L
Rhesus Macaque
Macaca mulatta
XP_001089576
1098
122550
Y868
S
L
L
S
A
Q
Q
Y
Q
E
M
E
G
N
L
Dog
Lupus familis
XP_541815
945
107213
Y715
S
L
L
S
A
Q
Q
Y
Q
E
M
E
G
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y24
845
95821
Y615
S
L
L
S
A
Q
Q
Y
Q
E
M
E
G
N
L
Rat
Rattus norvegicus
Q71QF9
831
94152
L602
L
K
S
L
N
S
E
L
C
P
E
K
I
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
Y652
S
L
L
S
A
Q
Q
Y
Q
D
M
E
G
N
L
Chicken
Gallus gallus
XP_001234704
864
97886
Q634
V
R
S
L
L
S
A
Q
Q
Y
Q
D
L
E
P
Frog
Xenopus laevis
Q90WV2
832
94675
I602
L
K
S
L
T
S
E
I
C
Q
E
K
P
P
P
Zebra Danio
Brachydanio rerio
NP_001071251
869
98168
I630
V
P
R
P
L
A
D
I
G
M
P
V
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
Q607
A
Q
Q
Q
Q
P
L
Q
Q
N
G
M
R
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.6
85.6
N.A.
95
50.3
N.A.
88.3
84
48.3
55
N.A.
N.A.
N.A.
N.A.
40.6
Protein Similarity:
100
100
76.8
87.9
N.A.
97.7
64.2
N.A.
92.2
90.1
63.3
69.1
N.A.
N.A.
N.A.
N.A.
54.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
20
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
55
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
10
% D
% Glu:
0
0
0
0
0
0
19
0
0
46
19
55
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
10
0
55
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
0
0
0
0
10
10
0
% I
% Lys:
0
19
0
0
0
0
0
0
0
0
0
19
0
0
0
% K
% Leu:
19
55
55
28
19
0
10
10
0
0
0
0
10
10
55
% L
% Met:
0
0
0
0
0
0
0
0
0
10
55
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
55
0
% N
% Pro:
0
10
0
10
0
10
0
0
0
10
10
0
10
19
28
% P
% Gln:
0
10
10
10
10
55
55
19
73
10
10
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
19
0
10
% R
% Ser:
55
0
28
55
0
28
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _