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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTCH2NL
All Species:
1.82
Human Site:
S73
Identified Species:
13.33
UniProt:
Q7Z3S9
Number Species:
3
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3S9
NP_982283.2
236
25835
S73
T
S
H
P
C
F
V
S
R
P
C
L
N
G
G
Chimpanzee
Pan troglodytes
XP_001157211
237
25869
Q82
D
T
Y
E
C
T
C
Q
V
G
F
T
G
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624262
464
49323
S90
P
L
E
N
A
C
D
S
S
P
C
L
N
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P49013
570
61097
P182
S
D
G
D
D
C
T
P
N
P
C
L
N
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
23
N.A.
22.4
Protein Similarity:
100
89.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.2
N.A.
27.8
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
33.3
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
50
50
25
0
0
0
75
0
0
0
0
% C
% Asp:
25
25
0
25
25
0
25
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
25
0
0
0
0
0
0
0
0
0
0
25
% E
% Phe:
0
0
0
0
0
25
0
0
0
0
25
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
0
0
0
25
0
0
25
75
25
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% K
% Leu:
0
25
0
0
0
0
0
0
0
0
0
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
0
0
0
25
0
0
0
75
0
0
% N
% Pro:
25
0
0
25
0
0
0
25
0
75
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% R
% Ser:
25
25
0
0
0
0
0
50
25
0
0
0
0
0
0
% S
% Thr:
25
25
0
0
0
25
25
0
0
0
0
25
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _