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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE16
All Species:
14.55
Human Site:
Y515
Identified Species:
40
UniProt:
Q7Z3T8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3T8
NP_001098721.1
1539
168849
Y515
M
D
G
Q
D
L
D
Y
F
N
I
D
E
G
A
Chimpanzee
Pan troglodytes
XP_001135982
1539
169040
Y515
M
D
G
Q
D
L
D
Y
F
N
I
D
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
Y516
M
D
G
Q
D
L
D
Y
F
N
I
D
E
G
T
Dog
Lupus familis
XP_536310
1516
166814
E495
P
E
F
P
D
S
C
E
G
F
P
F
S
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
Y504
M
D
G
Q
E
L
D
Y
F
N
I
D
E
S
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
D492
I
I
S
Q
V
L
E
D
F
N
I
D
D
A
I
Chicken
Gallus gallus
XP_424894
1103
120204
T143
S
A
G
A
N
V
D
T
Q
K
L
Q
P
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396901
1227
137615
D267
E
C
T
Y
I
Q
N
D
Y
Y
E
N
E
C
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
N532
G
N
D
N
E
L
A
N
V
D
P
F
Y
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.3
82.8
N.A.
73.4
N.A.
N.A.
59.5
27.3
N.A.
N.A.
N.A.
N.A.
30.1
N.A.
25.1
Protein Similarity:
100
99.3
96.3
88.7
N.A.
82
N.A.
N.A.
73.2
41.3
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
43.9
P-Site Identity:
100
100
93.3
6.6
N.A.
80
N.A.
N.A.
40
20
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
86.6
N.A.
N.A.
60
40
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
0
0
12
0
0
0
0
0
0
12
23
% A
% Cys:
0
12
0
0
0
0
12
0
0
0
0
0
0
12
0
% C
% Asp:
0
45
12
0
45
0
56
23
0
12
0
56
12
0
12
% D
% Glu:
12
12
0
0
23
0
12
12
0
0
12
0
56
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
56
12
0
23
0
0
0
% F
% Gly:
12
0
56
0
0
0
0
0
12
0
0
0
0
56
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
12
0
0
0
0
0
56
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
67
0
0
0
0
12
0
0
0
0
% L
% Met:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
12
0
12
12
0
12
12
0
56
0
12
0
0
12
% N
% Pro:
12
0
0
12
0
0
0
0
0
0
23
0
12
0
0
% P
% Gln:
0
0
0
56
0
12
0
0
12
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
12
0
0
12
0
0
0
0
0
0
12
23
0
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
23
% T
% Val:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
45
12
12
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _