KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3B
All Species:
22.73
Human Site:
S280
Identified Species:
38.46
UniProt:
Q7Z3V4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3V4
NP_569733.2
1068
123070
S280
E
R
L
T
V
L
E
S
H
D
M
L
R
K
F
Chimpanzee
Pan troglodytes
XP_509354
1068
122921
S280
E
R
L
T
V
L
E
S
H
D
M
L
R
K
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543437
1068
123121
S280
E
R
L
T
V
L
E
S
H
D
M
L
R
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES34
1070
122743
S280
E
R
L
G
V
L
E
S
H
D
M
L
R
K
F
Rat
Rattus norvegicus
NP_001137366
1070
122598
S280
E
R
L
G
V
L
E
S
H
D
M
L
R
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423951
837
96057
L129
L
S
K
D
L
T
L
L
W
I
K
Q
I
K
D
Frog
Xenopus laevis
Q6DCL5
944
106566
L233
D
K
N
G
V
T
P
L
D
L
C
V
Q
G
G
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L57
T
D
T
V
R
N
T
L
D
P
K
W
N
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Y264
D
A
N
G
R
T
Y
Y
V
N
H
T
A
R
T
Honey Bee
Apis mellifera
XP_392283
1063
121439
T279
V
C
I
S
S
F
I
T
N
N
L
F
A
R
S
Nematode Worm
Caenorhab. elegans
NP_499392
1066
120863
I275
E
L
L
K
T
T
K
I
F
E
K
T
L
H
W
Sea Urchin
Strong. purpuratus
XP_786887
582
66877
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
T274
S
F
S
S
M
I
L
T
I
P
L
I
W
K
L
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
Q202
E
K
R
P
F
A
L
Q
F
Y
C
I
L
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
96.5
N.A.
92.1
91.8
N.A.
N.A.
68.6
20.8
22.8
N.A.
20.4
51.5
37.6
37.1
Protein Similarity:
100
98.9
N.A.
98.5
N.A.
96
96.1
N.A.
N.A.
74
40.1
38.4
N.A.
37.1
69.1
58.4
44.9
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
33.3
6.6
N.A.
20
46.6
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
0
0
0
15
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
15
8
0
8
0
0
0
0
15
36
0
0
0
0
8
% D
% Glu:
50
0
0
0
0
0
36
0
0
8
0
0
0
0
8
% E
% Phe:
0
8
0
0
8
8
0
0
15
0
0
8
0
0
36
% F
% Gly:
0
0
0
29
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
36
0
8
0
0
8
8
% H
% Ile:
0
0
8
0
0
8
8
8
8
8
0
15
8
0
0
% I
% Lys:
0
15
8
8
0
0
8
0
0
0
22
0
0
50
0
% K
% Leu:
8
8
43
0
8
36
22
22
0
8
15
36
15
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
36
0
0
0
0
% M
% Asn:
0
0
15
0
0
8
0
0
8
15
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
8
8
0
% Q
% Arg:
0
36
8
0
15
0
0
0
0
0
0
0
36
15
0
% R
% Ser:
8
8
8
15
8
0
0
36
0
0
0
0
0
0
8
% S
% Thr:
8
0
8
22
8
29
8
15
0
0
0
15
0
0
8
% T
% Val:
8
0
0
8
43
0
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
8
% W
% Tyr:
0
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _