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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT25
All Species:
21.82
Human Site:
S406
Identified Species:
60
UniProt:
Q7Z3Z0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z0
NP_853512.1
450
49318
S406
Y
K
S
K
D
Y
G
S
G
N
V
G
S
Q
V
Chimpanzee
Pan troglodytes
A5A6N2
450
49288
S406
Y
K
S
K
D
Y
G
S
G
N
V
G
S
Q
V
Rhesus Macaque
Macaca mulatta
XP_001100293
450
49129
S406
Y
K
S
K
D
Y
G
S
G
N
V
G
S
Q
V
Dog
Lupus familis
XP_548129
1272
139214
V406
G
S
C
G
L
S
G
V
S
S
S
G
F
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCW2
446
48903
S402
Y
K
S
K
D
Y
G
S
G
N
A
G
N
Q
I
Rat
Rattus norvegicus
Q6IFX0
446
48925
S402
Y
K
S
K
D
Y
T
S
G
N
A
G
N
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520523
449
49180
S405
F
K
S
T
G
Y
A
S
G
V
L
A
S
Q
L
Chicken
Gallus gallus
Q6PVZ1
467
50967
H431
Y
S
S
A
M
S
S
H
S
G
R
D
A
I
T
Frog
Xenopus laevis
P08777
429
47223
T391
Q
V
T
T
V
A
N
T
S
S
V
E
S
K
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.1
32.7
N.A.
91.1
90
N.A.
84.8
47.3
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
97.5
33.7
N.A.
94.2
93.1
N.A.
90.2
64.4
63.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
80
73.3
N.A.
46.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
80
N.A.
66.6
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
12
0
0
0
23
12
12
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
56
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
12
0
0
12
12
0
56
0
67
12
0
67
0
12
12
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% I
% Lys:
0
67
0
56
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
12
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
56
0
0
23
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
0
23
78
0
0
23
12
67
34
23
12
0
56
0
12
% S
% Thr:
0
0
12
23
0
0
12
12
0
0
0
0
0
0
23
% T
% Val:
0
12
0
0
12
0
0
12
0
12
45
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _