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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL3 All Species: 27.88
Human Site: S116 Identified Species: 51.11
UniProt: Q7Z3Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3Z3 NP_001008496.2 882 101089 S116 D M K H V K D S K T G S E G T
Chimpanzee Pan troglodytes XP_528661 878 100916 S112 D M K H V K D S K T G S E G T
Rhesus Macaque Macaca mulatta XP_001099093 882 101146 S116 Y M M H V K D S K T G S E G T
Dog Lupus familis XP_534638 861 98542 S103 N L D H V K E S K T G S S G I
Cat Felis silvestris
Mouse Mus musculus Q9JMB7 862 98556 S104 N L D H V K E S K T G S S G I
Rat Rattus norvegicus Q4G033 848 95953 V101 T G S S G I P V Q L A T N L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 S422 G I E H V Q E S K T G S S G I
Chicken Gallus gallus A6N7Y9 867 99268 S111 A I E H V R E S K T G S S G A
Frog Xenopus laevis Q6DCX2 862 97626 N101 P V F D G R K N L Y T A M P L
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 S101 L M E H V K E S K T G V S G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 T101 G V P V M L Q T N F F R L K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 V98 T T R P E N F V K Q A I A G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJK3 997 111116 P151 A V T F P V R P G R G T L G K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.1 50.2 N.A. 50 39.4 N.A. 38.9 48.1 21.4 45.5 N.A. 32.9 N.A. N.A. 38.5
Protein Similarity: 100 99.3 96.9 67 N.A. 67 58.6 N.A. 52.5 66.7 41.2 63.2 N.A. 53.8 N.A. N.A. 57.7
P-Site Identity: 100 100 86.6 60 N.A. 60 0 N.A. 53.3 53.3 0 66.6 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 86.6 80 N.A. 80 13.3 N.A. 80 80 26.6 80 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 0 0 0 0 0 16 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 16 8 0 0 24 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 24 0 8 0 39 0 0 0 0 0 24 0 0 % E
% Phe: 0 0 8 8 0 0 8 0 0 8 8 0 0 0 8 % F
% Gly: 16 8 0 0 16 0 0 0 8 0 70 0 0 77 0 % G
% His: 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 0 8 0 0 0 0 0 8 0 0 24 % I
% Lys: 0 0 16 0 0 47 8 0 70 0 0 0 0 8 8 % K
% Leu: 8 16 0 0 0 8 0 0 8 8 0 0 16 8 8 % L
% Met: 0 31 8 0 8 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 16 0 0 0 0 8 0 8 8 0 0 0 8 0 0 % N
% Pro: 8 0 8 8 8 0 8 8 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 8 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 16 8 0 0 8 0 8 0 0 0 % R
% Ser: 0 0 8 8 0 0 0 62 0 0 0 54 39 0 0 % S
% Thr: 16 8 8 0 0 0 0 8 0 62 8 16 0 0 39 % T
% Val: 0 24 0 8 62 8 0 16 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _