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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
10
Human Site:
S218
Identified Species:
18.33
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
S218
S
K
E
L
T
P
T
S
P
D
C
L
R
Y
Y
Chimpanzee
Pan troglodytes
XP_528661
878
100916
S214
S
K
E
L
T
P
T
S
P
D
C
L
R
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
S218
S
K
E
I
R
P
T
S
P
D
C
L
R
Y
Y
Dog
Lupus familis
XP_534638
861
98542
P203
T
L
T
N
E
L
P
P
T
S
P
T
C
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
P204
T
L
T
N
E
L
P
P
T
S
P
T
C
L
Q
Rat
Rattus norvegicus
Q4G033
848
95953
F200
N
S
P
M
C
I
Q
F
F
N
V
I
F
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
P522
T
L
T
N
E
L
P
P
T
S
P
T
C
L
Q
Chicken
Gallus gallus
A6N7Y9
867
99268
P211
T
L
T
N
E
L
P
P
T
S
P
T
C
L
Q
Frog
Xenopus laevis
Q6DCX2
862
97626
R199
A
N
P
L
G
G
G
R
E
V
W
F
G
F
H
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
P201
T
L
T
N
E
L
P
P
S
S
P
V
C
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
N198
P
R
F
L
Q
V
L
N
L
I
L
R
R
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
N197
V
T
H
V
A
T
L
N
P
M
A
P
N
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
T284
Q
R
E
A
P
Y
D
T
I
Q
V
L
D
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
86.6
0
N.A.
0
0
N.A.
0
0
6.6
0
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
6.6
N.A.
6.6
26.6
N.A.
6.6
6.6
26.6
13.3
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
24
0
39
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
24
0
0
8
0
0
% D
% Glu:
0
0
31
0
39
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
0
8
8
8
0
% F
% Gly:
0
0
0
0
8
8
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
8
0
0
8
8
0
8
0
0
0
% I
% Lys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
39
0
31
0
39
16
0
8
0
8
31
0
39
8
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
8
8
0
39
0
0
0
16
0
8
0
0
8
0
0
% N
% Pro:
8
0
16
0
8
24
39
39
31
0
39
8
0
0
0
% P
% Gln:
8
0
0
0
8
0
8
0
0
8
0
0
0
0
39
% Q
% Arg:
0
16
0
0
8
0
0
8
0
0
0
8
31
8
0
% R
% Ser:
24
8
0
0
0
0
0
24
8
39
0
0
0
8
0
% S
% Thr:
39
8
39
0
16
8
24
8
31
0
0
31
0
8
0
% T
% Val:
8
0
0
8
0
8
0
0
0
8
16
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
24
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _