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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
10.61
Human Site:
S32
Identified Species:
19.44
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
S32
G
G
P
R
A
P
G
S
A
T
T
Q
E
P
P
Chimpanzee
Pan troglodytes
XP_528661
878
100916
S32
G
G
P
R
A
P
G
S
A
T
T
Q
E
P
A
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
S32
G
G
P
G
A
P
G
S
A
T
V
S
P
P
T
Dog
Lupus familis
XP_534638
861
98542
Y32
T
V
S
Q
Q
P
G
Y
V
Q
P
R
P
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
Y32
A
A
S
Q
Q
P
G
Y
I
P
P
R
P
Q
Q
Rat
Rattus norvegicus
Q4G033
848
95953
S32
P
R
D
L
M
V
T
S
V
S
P
G
D
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
F74
E
L
L
N
I
L
G
F
P
T
A
T
I
R
I
Chicken
Gallus gallus
A6N7Y9
867
99268
L32
A
A
S
A
Q
K
T
L
P
S
H
P
S
E
Q
Frog
Xenopus laevis
Q6DCX2
862
97626
F33
K
P
P
P
R
P
D
F
G
T
S
G
R
T
I
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
A32
P
P
V
S
Q
E
A
A
K
P
V
V
S
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
F33
D
G
P
R
V
K
V
F
R
G
S
S
S
G
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
G32
G
M
P
V
P
G
R
G
R
S
R
G
G
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
L38
G
Q
V
A
W
P
G
L
Q
Q
S
Y
G
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
93.3
66.6
13.3
N.A.
13.3
6.6
N.A.
13.3
0
20
6.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
66.6
26.6
N.A.
26.6
20
N.A.
13.3
6.6
26.6
13.3
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
16
24
0
8
8
24
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
8
0
0
0
0
0
8
0
8
% D
% Glu:
8
0
0
0
0
8
0
0
0
0
0
0
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
39
31
0
8
0
8
54
8
8
8
0
24
16
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
16
% I
% Lys:
8
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
0
8
0
16
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
16
16
47
8
8
54
0
0
16
16
24
8
24
24
16
% P
% Gln:
0
8
0
16
31
0
0
0
8
16
0
16
0
16
24
% Q
% Arg:
0
8
0
24
8
0
8
0
16
0
8
16
8
8
8
% R
% Ser:
0
0
24
8
0
0
0
31
0
24
24
16
24
0
0
% S
% Thr:
8
0
0
0
0
0
16
0
0
39
16
8
0
24
16
% T
% Val:
0
8
16
8
8
8
8
0
16
0
16
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _