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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
25.76
Human Site:
S379
Identified Species:
47.22
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
S379
K
K
Q
P
L
L
V
S
Q
G
R
W
K
K
G
Chimpanzee
Pan troglodytes
XP_528661
878
100916
S375
K
K
Q
P
L
L
V
S
Q
G
R
W
K
K
G
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
S379
K
K
Q
P
L
L
V
S
Q
G
R
W
K
K
G
Dog
Lupus familis
XP_534638
861
98542
S364
L
K
Q
P
V
L
V
S
Q
P
K
R
R
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
S365
L
K
Q
P
V
L
V
S
Q
P
K
R
R
R
G
Rat
Rattus norvegicus
Q4G033
848
95953
D361
L
L
K
R
R
R
N
D
N
S
E
P
Q
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
S683
L
K
Q
P
V
L
V
S
Q
P
K
R
R
R
G
Chicken
Gallus gallus
A6N7Y9
867
99268
S372
L
N
Q
P
V
L
I
S
Q
Y
R
R
K
R
G
Frog
Xenopus laevis
Q6DCX2
862
97626
T360
Q
R
C
I
K
K
L
T
D
N
Q
T
S
T
M
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
H362
N
Q
V
L
L
V
S
H
V
K
R
L
G
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
E359
A
L
K
T
N
A
S
E
L
V
V
L
I
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
R358
N
Q
P
M
L
V
S
R
P
K
K
R
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
Y445
K
Y
N
Y
R
V
K
Y
Q
A
L
P
A
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
100
53.3
N.A.
53.3
0
N.A.
53.3
53.3
0
13.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
80
13.3
N.A.
80
73.3
33.3
26.6
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
8
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
24
0
0
8
0
54
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
31
47
16
0
8
8
8
0
0
16
31
0
31
24
8
% K
% Leu:
39
16
0
8
39
54
8
0
8
0
8
16
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
16
8
8
0
8
0
8
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
8
54
0
0
0
0
8
24
0
16
0
16
0
% P
% Gln:
8
16
54
0
0
0
0
0
62
0
8
0
8
0
8
% Q
% Arg:
0
8
0
8
16
8
0
8
0
0
39
39
24
31
0
% R
% Ser:
0
0
0
0
0
0
24
54
0
8
0
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
8
0
8
0
% T
% Val:
0
0
8
0
31
24
47
0
8
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _