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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL3 All Species: 4.24
Human Site: S43 Identified Species: 7.78
UniProt: Q7Z3Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3Z3 NP_001008496.2 882 101089 S43 Q E P P Q L Q S T P R P L Q E
Chimpanzee Pan troglodytes XP_528661 878 100916 S43 Q E P A Q L Q S T P R P L Q E
Rhesus Macaque Macaca mulatta XP_001099093 882 101146 R43 S P P T Q L Q R T P R P L R E
Dog Lupus familis XP_534638 861 98542 E43 R P Q Q P V A E G E L V G R G
Cat Felis silvestris
Mouse Mus musculus Q9JMB7 862 98556 E43 R P Q Q S P T E G D L V G R G
Rat Rattus norvegicus Q4G033 848 95953 R43 G D N E A S S R T S V I S Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 L85 T I R I T N R L S P R P A Q Q
Chicken Gallus gallus A6N7Y9 867 99268 L43 P S E Q R Q S L Q P C H P P P
Frog Xenopus laevis Q6DCX2 862 97626 A44 G R T I K L Q A N V F E M D I
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 Q43 V S T P S E G Q L V G R G R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 D44 S S G D P R A D P R I E A S R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 P43 G G T T Q P G P G A V P K Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJK3 997 111116 V49 Y G G R G G S V S A G R G R G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.1 50.2 N.A. 50 39.4 N.A. 38.9 48.1 21.4 45.5 N.A. 32.9 N.A. N.A. 38.5
Protein Similarity: 100 99.3 96.9 67 N.A. 67 58.6 N.A. 52.5 66.7 41.2 63.2 N.A. 53.8 N.A. N.A. 57.7
P-Site Identity: 100 93.3 66.6 0 N.A. 0 13.3 N.A. 26.6 6.6 13.3 6.6 N.A. 0 N.A. N.A. 26.6
P-Site Similarity: 100 93.3 73.3 20 N.A. 13.3 20 N.A. 46.6 13.3 33.3 20 N.A. 0 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 16 8 0 16 0 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 8 0 8 0 0 0 8 0 % D
% Glu: 0 16 8 8 0 8 0 16 0 8 0 16 0 0 31 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 24 16 16 0 8 8 16 0 24 0 16 0 31 0 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 16 0 0 0 0 0 0 8 8 0 0 8 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 0 31 0 16 8 0 16 0 24 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 24 24 16 16 16 0 8 8 39 0 39 8 8 16 % P
% Gln: 16 0 16 24 31 8 31 8 8 0 0 0 0 39 16 % Q
% Arg: 16 8 8 8 8 8 8 16 0 8 31 16 0 39 8 % R
% Ser: 16 24 0 0 16 8 24 16 16 8 0 0 8 8 0 % S
% Thr: 8 0 24 16 8 0 8 0 31 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 8 0 8 0 16 16 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _