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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
23.33
Human Site:
S466
Identified Species:
42.78
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
S466
K
F
D
T
N
F
L
S
V
P
G
R
V
L
K
Chimpanzee
Pan troglodytes
XP_528661
878
100916
S462
K
F
D
T
N
F
L
S
V
P
G
R
V
L
K
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
S466
K
F
D
T
N
F
L
S
V
S
G
R
V
L
K
Dog
Lupus familis
XP_534638
861
98542
S451
S
F
D
S
N
L
L
S
F
S
G
R
I
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
S452
S
F
D
S
N
L
L
S
F
S
G
R
I
L
Q
Rat
Rattus norvegicus
Q4G033
848
95953
V443
Q
L
S
L
T
G
R
V
V
P
S
E
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
A770
S
F
D
S
N
L
L
A
F
S
G
R
I
M
Q
Chicken
Gallus gallus
A6N7Y9
867
99268
S457
S
F
D
S
S
L
L
S
F
T
G
R
V
V
Q
Frog
Xenopus laevis
Q6DCX2
862
97626
N442
Q
G
V
W
D
M
R
N
K
Q
F
H
T
G
I
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
S448
S
F
E
N
K
L
L
S
L
N
G
R
V
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
Q441
Q
G
R
I
I
G
Q
Q
N
I
V
F
H
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
K442
E
F
D
K
E
Q
V
K
L
T
G
R
V
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
S529
S
V
T
T
Q
L
A
S
I
E
A
R
V
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
93.3
53.3
N.A.
53.3
13.3
N.A.
40
46.6
0
46.6
N.A.
0
N.A.
N.A.
40
P-Site Similarity:
100
100
93.3
73.3
N.A.
73.3
26.6
N.A.
73.3
73.3
20
60
N.A.
6.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
62
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
70
0
0
0
24
0
0
31
0
8
8
0
0
0
% F
% Gly:
0
16
0
0
0
16
0
0
0
0
70
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
8
8
0
0
24
8
8
% I
% Lys:
24
0
0
8
8
0
0
8
8
0
0
0
8
0
24
% K
% Leu:
0
8
0
8
0
47
62
0
16
0
0
0
0
62
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
47
0
0
8
8
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
24
% P
% Gln:
24
0
0
0
8
8
8
8
0
8
0
0
0
0
31
% Q
% Arg:
0
0
8
0
0
0
16
0
0
0
0
77
0
0
0
% R
% Ser:
47
0
8
31
8
0
0
62
0
31
8
0
0
0
0
% S
% Thr:
0
0
8
31
8
0
0
0
0
16
0
0
8
0
0
% T
% Val:
0
8
8
0
0
0
8
8
31
0
8
0
54
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _