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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
12.42
Human Site:
S554
Identified Species:
22.78
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
S554
E
V
D
G
D
A
N
S
Y
I
D
T
L
R
K
Chimpanzee
Pan troglodytes
XP_528661
878
100916
S550
E
V
D
G
D
A
N
S
Y
I
D
T
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
S554
E
V
D
G
D
A
N
S
Y
I
D
T
L
R
K
Dog
Lupus familis
XP_534638
861
98542
A540
E
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
A541
E
V
D
D
R
T
E
A
Y
L
R
A
L
Q
Q
Rat
Rattus norvegicus
Q4G033
848
95953
A526
K
V
D
E
N
P
A
A
F
L
R
A
I
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
A859
E
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
Chicken
Gallus gallus
A6N7Y9
867
99268
A546
E
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
Frog
Xenopus laevis
Q6DCX2
862
97626
T529
V
V
I
L
P
G
K
T
P
V
Y
A
E
V
K
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
S537
E
Y
E
D
R
Q
E
S
L
L
R
A
L
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
G522
I
I
Y
D
D
R
T
G
T
Y
V
R
A
M
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
E531
E
L
P
D
D
R
T
E
T
Y
T
R
S
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
P613
F
K
P
Q
P
A
I
P
F
I
S
C
P
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
100
33.3
N.A.
33.3
13.3
N.A.
33.3
33.3
13.3
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
60
N.A.
60
60
N.A.
60
60
26.6
46.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
8
39
0
0
0
31
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
62
54
39
0
0
0
0
0
24
0
0
0
8
% D
% Glu:
70
0
8
8
0
0
39
8
0
0
0
0
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% F
% Gly:
0
0
0
24
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
8
0
0
31
0
0
8
0
0
% I
% Lys:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
31
% K
% Leu:
0
8
0
8
0
0
0
0
8
47
0
0
62
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
24
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
0
16
8
0
8
8
0
0
0
8
8
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
0
0
47
47
% Q
% Arg:
0
0
0
0
39
16
0
0
0
0
47
16
0
24
0
% R
% Ser:
0
0
0
0
0
0
0
31
0
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
31
16
8
16
0
8
24
0
0
0
% T
% Val:
8
70
0
0
0
0
0
0
0
8
8
24
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
54
16
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _