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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
10.3
Human Site:
T259
Identified Species:
18.89
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
T259
I
Q
L
Y
R
H
G
T
S
L
E
I
W
L
G
Chimpanzee
Pan troglodytes
XP_528661
878
100916
T255
I
Q
L
Y
R
H
G
T
S
L
E
I
W
L
G
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
T259
I
Q
L
Y
R
H
G
T
S
L
E
I
W
L
G
Dog
Lupus familis
XP_534638
861
98542
H244
D
P
I
D
I
P
N
H
R
L
V
I
W
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
H245
D
P
I
D
I
P
N
H
R
L
V
I
W
P
G
Rat
Rattus norvegicus
Q4G033
848
95953
F241
K
L
S
L
W
P
G
F
A
I
S
V
S
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
H563
D
P
I
S
I
P
N
H
R
L
V
I
W
P
G
Chicken
Gallus gallus
A6N7Y9
867
99268
H252
D
P
V
S
I
P
N
H
R
L
M
V
W
P
G
Frog
Xenopus laevis
Q6DCX2
862
97626
V240
V
I
E
F
M
C
E
V
L
D
F
K
S
I
E
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
H242
D
P
F
N
I
P
Q
H
R
L
T
I
W
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
T239
E
L
W
P
G
Y
E
T
S
I
R
Q
H
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
Q238
T
A
A
I
D
I
K
Q
H
G
L
Q
L
W
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
D325
D
G
R
G
E
L
G
D
G
I
E
Y
W
R
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
100
26.6
N.A.
26.6
6.6
N.A.
26.6
20
0
26.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
26.6
N.A.
33.3
33.3
20
26.6
N.A.
26.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
16
8
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
8
0
8
0
8
0
16
0
0
0
31
0
0
8
8
% E
% Phe:
0
0
8
8
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
0
8
0
8
8
0
39
0
8
8
0
0
0
0
70
% G
% His:
0
0
0
0
0
24
0
39
8
0
0
0
8
0
0
% H
% Ile:
24
8
24
8
39
8
0
0
0
24
0
54
0
8
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% K
% Leu:
0
16
24
8
0
8
0
0
8
62
8
0
8
24
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
31
0
0
0
0
0
0
0
0
% N
% Pro:
0
39
0
8
0
47
0
0
0
0
0
0
0
39
8
% P
% Gln:
0
24
0
0
0
0
8
8
0
0
0
16
0
0
0
% Q
% Arg:
0
0
8
0
24
0
0
0
39
0
8
0
0
16
0
% R
% Ser:
0
0
8
16
0
0
0
0
31
0
8
0
16
0
0
% S
% Thr:
8
0
0
0
0
0
0
31
0
0
8
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
8
0
0
24
16
0
0
0
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
0
70
8
0
% W
% Tyr:
0
0
0
24
0
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _