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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
12.73
Human Site:
T435
Identified Species:
23.33
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
T435
S
P
R
R
R
H
H
T
L
K
E
F
I
N
T
Chimpanzee
Pan troglodytes
XP_528661
878
100916
T431
S
P
R
R
R
H
H
T
L
K
E
F
I
N
T
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
T435
S
P
R
R
R
H
H
T
L
K
E
F
I
N
T
Dog
Lupus familis
XP_534638
861
98542
E420
T
P
E
Q
R
Q
R
E
V
G
R
L
I
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
E421
T
P
E
Q
R
Q
R
E
V
G
R
L
I
D
Y
Rat
Rattus norvegicus
Q4G033
848
95953
Q417
A
R
L
A
D
D
I
Q
R
N
Q
V
T
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
E739
T
P
E
Q
R
Q
R
E
V
G
R
L
I
D
Y
Chicken
Gallus gallus
A6N7Y9
867
99268
G428
E
Q
R
Q
R
E
I
G
K
L
V
D
C
M
K
Frog
Xenopus laevis
Q6DCX2
862
97626
L416
T
D
V
T
G
R
V
L
Q
P
P
S
I
L
Y
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
I418
P
E
Q
R
E
G
R
I
N
R
L
I
S
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
S415
R
L
Q
N
T
P
E
S
V
K
V
L
R
D
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
G414
D
R
C
R
T
L
S
G
F
I
K
K
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
S501
R
P
P
D
R
E
N
S
I
K
N
L
V
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
100
20
N.A.
20
0
N.A.
20
13.3
6.6
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
13.3
N.A.
46.6
20
13.3
26.6
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
0
8
8
8
0
0
0
0
0
8
0
31
0
% D
% Glu:
8
8
24
0
8
16
8
24
0
0
24
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
24
0
0
8
% F
% Gly:
0
0
0
0
8
8
0
16
0
24
0
0
0
0
0
% G
% His:
0
0
0
0
0
24
24
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
8
8
8
0
8
54
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
39
8
8
0
0
16
% K
% Leu:
0
8
8
0
0
8
0
8
24
8
8
39
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
8
0
8
8
8
0
0
31
0
% N
% Pro:
8
54
8
0
0
8
0
0
0
8
8
0
0
0
0
% P
% Gln:
0
8
16
31
0
24
0
8
8
0
8
0
0
0
0
% Q
% Arg:
16
16
31
39
62
8
31
0
8
8
24
0
8
8
0
% R
% Ser:
24
0
0
0
0
0
8
16
0
0
0
8
8
8
8
% S
% Thr:
31
0
0
8
16
0
0
24
0
0
0
0
8
0
24
% T
% Val:
0
0
8
0
0
0
8
0
31
0
16
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _