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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL3
All Species:
9.39
Human Site:
Y745
Identified Species:
17.22
UniProt:
Q7Z3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Z3
NP_001008496.2
882
101089
Y745
E
A
K
K
M
S
T
Y
L
K
T
I
S
P
N
Chimpanzee
Pan troglodytes
XP_528661
878
100916
Y741
E
A
K
K
M
S
T
Y
L
K
T
I
S
P
N
Rhesus Macaque
Macaca mulatta
XP_001099093
882
101146
Y745
E
A
K
K
M
S
T
Y
L
K
T
L
S
P
N
Dog
Lupus familis
XP_534638
861
98542
L724
V
P
Q
F
L
D
C
L
K
S
V
G
R
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
L725
V
P
Q
F
L
D
C
L
K
S
V
G
R
G
Y
Rat
Rattus norvegicus
Q4G033
848
95953
T711
P
Q
L
L
S
S
V
T
E
C
G
S
D
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
L1043
V
P
Q
F
L
D
C
L
K
S
V
G
E
D
Y
Chicken
Gallus gallus
A6N7Y9
867
99268
L730
V
P
Q
F
L
D
C
L
K
T
V
G
K
D
Y
Frog
Xenopus laevis
Q6DCX2
862
97626
E698
R
E
A
C
I
K
L
E
K
D
Y
Q
P
G
I
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
I721
V
P
Q
I
M
Q
S
I
K
T
M
G
Q
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
K706
E
V
K
D
I
I
E
K
L
K
T
E
Y
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
D717
K
Q
I
K
D
T
L
D
K
V
Y
P
Q
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
N835
A
C
N
S
L
Q
E
N
Y
V
P
R
V
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
50.2
N.A.
50
39.4
N.A.
38.9
48.1
21.4
45.5
N.A.
32.9
N.A.
N.A.
38.5
Protein Similarity:
100
99.3
96.9
67
N.A.
67
58.6
N.A.
52.5
66.7
41.2
63.2
N.A.
53.8
N.A.
N.A.
57.7
P-Site Identity:
100
100
93.3
0
N.A.
0
6.6
N.A.
0
0
0
6.6
N.A.
33.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
6.6
N.A.
13.3
13.3
6.6
20
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
0
0
0
0
0
0
0
0
0
0
16
0
% A
% Cys:
0
8
0
8
0
0
31
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
31
0
8
0
8
0
0
8
24
0
% D
% Glu:
31
8
0
0
0
0
16
8
8
0
0
8
8
0
0
% E
% Phe:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
39
0
31
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
16
8
0
8
0
0
0
16
0
0
8
% I
% Lys:
8
0
31
31
0
8
0
8
54
31
0
0
8
0
0
% K
% Leu:
0
0
8
8
39
0
16
31
31
0
0
8
0
0
0
% L
% Met:
0
0
0
0
31
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
24
% N
% Pro:
8
39
0
0
0
0
0
0
0
0
8
8
8
24
0
% P
% Gln:
0
16
39
0
0
16
0
0
0
0
0
8
16
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
16
0
16
% R
% Ser:
0
0
0
8
8
31
8
0
0
24
0
8
24
0
0
% S
% Thr:
0
0
0
0
0
8
24
8
0
16
31
0
0
8
8
% T
% Val:
39
8
0
0
0
0
8
0
0
16
31
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
8
0
16
0
8
0
39
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _