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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL4 All Species: 20.61
Human Site: S567 Identified Species: 37.78
UniProt: Q7Z3Z4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3Z4 NP_689644.2 852 96589 S567 D S I K K Y L S S D C P V P S
Chimpanzee Pan troglodytes XP_508702 852 96725 S567 D S I K K Y L S S D C P V P S
Rhesus Macaque Macaca mulatta XP_001089264 852 96294 S567 D S I K K Y L S S D C P V P S
Dog Lupus familis XP_542241 929 105208 N644 D S I K K Y L N S F C P V P S
Cat Felis silvestris
Mouse Mus musculus Q8CGT6 848 95755 S562 D S I K K Y L S S D C P V P S
Rat Rattus norvegicus Q4G033 848 95953 S562 D S I K R Y L S S D C P V P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 C895 D A I K K Y L C T D C P T P S
Chicken Gallus gallus A6N7Y9 867 99268 C582 D A I K K Y L C T D C P I P S
Frog Xenopus laevis Q6DCX2 862 97626 K573 L C L K I N V K L G G V N N I
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 C573 D C V K K Y L C V D C P T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 Y559 S S I K K R G Y V D R A V P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 V568 D A I K K T C V V T H P C P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04379 1048 116172 E697 G D L K R I C E T E L G I V S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.6 75.3 N.A. 77.6 76.8 N.A. 38.3 48.6 21.6 47.4 N.A. 33.7 N.A. N.A. 40.1
Protein Similarity: 100 99.8 99.3 83.6 N.A. 88.1 86.7 N.A. 52.1 67.8 43 67.1 N.A. 53.8 N.A. N.A. 59.3
P-Site Identity: 100 100 100 86.6 N.A. 100 93.3 N.A. 73.3 73.3 6.6 66.6 N.A. 46.6 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 86.6 93.3 20 73.3 N.A. 53.3 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 16 0 0 0 0 16 24 0 0 70 0 8 0 0 % C
% Asp: 77 8 0 0 0 0 0 0 0 70 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 0 8 8 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 77 0 8 8 0 0 0 0 0 0 16 0 8 % I
% Lys: 0 0 0 100 77 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 0 16 0 0 0 70 0 8 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 77 0 85 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 16 8 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 54 0 0 0 0 0 39 47 0 0 0 0 0 85 % S
% Thr: 0 0 0 0 0 8 0 0 24 8 0 0 16 0 8 % T
% Val: 0 0 8 0 0 0 8 8 24 0 0 8 54 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 70 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _