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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL4 All Species: 16.97
Human Site: S714 Identified Species: 31.11
UniProt: Q7Z3Z4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3Z4 NP_689644.2 852 96589 S714 E V P Q L L S S V A E S S S N
Chimpanzee Pan troglodytes XP_508702 852 96725 S714 E V P Q L L S S V A E S S S N
Rhesus Macaque Macaca mulatta XP_001089264 852 96294 S714 E V P Q L L S S V A E S S S N
Dog Lupus familis XP_542241 929 105208 S791 E V P Q L L S S V T E A S S N
Cat Felis silvestris
Mouse Mus musculus Q8CGT6 848 95755 V710 V P Q L L K S V T E C G S D A
Rat Rattus norvegicus Q4G033 848 95953 V710 V P Q L L S S V T E C G S D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 C1042 E V P Q F L D C L K S V G E D
Chicken Gallus gallus A6N7Y9 867 99268 C729 E V P Q F L D C L K T V G K D
Frog Xenopus laevis Q6DCX2 862 97626 T721 H H T R L F C T D R N E R V G
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 S720 E V P Q I M Q S I K T M G Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 E705 F E V K D I I E K L K T E Y A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 L716 L K Q I K D T L D K V Y P Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04379 1048 116172 A873 K A C A S L E A G Y Q P P V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.6 75.3 N.A. 77.6 76.8 N.A. 38.3 48.6 21.6 47.4 N.A. 33.7 N.A. N.A. 40.1
Protein Similarity: 100 99.8 99.3 83.6 N.A. 88.1 86.7 N.A. 52.1 67.8 43 67.1 N.A. 53.8 N.A. N.A. 59.3
P-Site Identity: 100 100 100 86.6 N.A. 20 20 N.A. 33.3 33.3 6.6 33.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 20 20 N.A. 46.6 46.6 20 60 N.A. 26.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 8 0 24 0 8 0 0 24 % A
% Cys: 0 0 8 0 0 0 8 16 0 0 16 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 16 0 16 0 0 0 0 16 24 % D
% Glu: 54 8 0 0 0 0 8 8 0 16 31 8 8 8 0 % E
% Phe: 8 0 0 0 16 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 16 24 0 16 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 8 8 0 8 0 0 0 0 0 0 % I
% Lys: 8 8 0 8 8 8 0 0 8 31 8 0 0 8 0 % K
% Leu: 8 0 0 16 54 54 0 8 16 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 31 % N
% Pro: 0 16 54 0 0 0 0 0 0 0 0 8 16 0 0 % P
% Gln: 0 0 24 54 0 0 8 0 0 0 8 0 0 16 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 0 0 0 0 8 8 47 39 0 0 8 24 47 31 0 % S
% Thr: 0 0 8 0 0 0 8 8 16 8 16 8 0 0 8 % T
% Val: 16 54 8 0 0 0 0 16 31 0 8 16 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _