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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL4 All Species: 9.09
Human Site: S724 Identified Species: 16.67
UniProt: Q7Z3Z4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3Z4 NP_689644.2 852 96589 S724 E S S S N T S S R L S V I V V
Chimpanzee Pan troglodytes XP_508702 852 96725 S724 E S S S N T S S R L S V I V V
Rhesus Macaque Macaca mulatta XP_001089264 852 96294 S724 E S S S N T S S R L S V I V V
Dog Lupus familis XP_542241 929 105208 P801 E A S S N T S P K L S V I V V
Cat Felis silvestris
Mouse Mus musculus Q8CGT6 848 95755 C720 C G S D A R S C R L S V V V V
Rat Rattus norvegicus Q4G033 848 95953 C720 C G S D A R S C R L S V V V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 P1052 S V G E D Y S P K L T V I V V
Chicken Gallus gallus A6N7Y9 867 99268 P739 T V G K D Y N P R L T V I V V
Frog Xenopus laevis Q6DCX2 862 97626 G731 N E R V G K S G N I P A G T T
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 P730 T M G Q D Y E P K L S V V V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 Q715 K T E Y A R V Q L S P P Q L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 H726 V Y P Q G T V H K L A V V V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04379 1048 116172 V883 Q P P V T F V V V Q K R H H T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.6 75.3 N.A. 77.6 76.8 N.A. 38.3 48.6 21.6 47.4 N.A. 33.7 N.A. N.A. 40.1
Protein Similarity: 100 99.8 99.3 83.6 N.A. 88.1 86.7 N.A. 52.1 67.8 43 67.1 N.A. 53.8 N.A. N.A. 59.3
P-Site Identity: 100 100 100 80 N.A. 53.3 53.3 N.A. 40 40 6.6 33.3 N.A. 0 N.A. N.A. 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 60 60 N.A. 60 60 13.3 53.3 N.A. 20 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 24 0 0 0 0 0 8 8 0 0 8 % A
% Cys: 16 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 24 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 31 8 8 8 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 16 24 0 16 0 0 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 47 0 0 % I
% Lys: 8 0 0 8 0 8 0 0 31 0 8 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 77 0 0 0 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 31 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 0 8 16 0 0 0 0 31 0 0 16 8 0 0 0 % P
% Gln: 8 0 0 16 0 0 0 8 0 8 0 0 8 0 0 % Q
% Arg: 0 0 8 0 0 24 0 0 47 0 0 8 0 0 0 % R
% Ser: 8 24 47 31 0 0 62 24 0 8 54 0 0 0 0 % S
% Thr: 16 8 0 0 8 39 0 0 0 0 16 0 0 8 16 % T
% Val: 8 16 0 16 0 0 24 8 8 0 0 77 31 77 77 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 24 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _