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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC6
All Species:
4.24
Human Site:
S75
Identified Species:
10.37
UniProt:
Q7Z403
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z403
NP_001120670.1
805
90045
S75
W
R
P
E
G
T
Q
S
T
A
T
L
R
I
L
Chimpanzee
Pan troglodytes
XP_001153587
647
75381
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540460
783
87776
D75
Q
T
L
L
G
P
E
D
P
L
V
H
S
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN60
810
90527
S74
L
E
G
A
P
A
L
S
S
A
T
L
R
I
L
Rat
Rattus norvegicus
Q5M7W4
965
110699
S92
N
T
R
C
H
P
R
S
A
H
P
R
T
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
Y103
G
S
R
D
Y
P
D
Y
P
G
S
R
D
Y
P
Chicken
Gallus gallus
Q5YCC5
735
84359
S69
G
N
L
R
G
I
A
S
A
E
R
R
E
P
Q
Frog
Xenopus laevis
NP_001085652
725
84100
Q63
I
S
D
A
Q
E
E
Q
Q
R
L
L
V
S
E
Zebra Danio
Brachydanio rerio
XP_689991
670
76642
P8
M
R
R
M
S
V
Y
P
Q
H
G
T
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
P98
F
S
G
S
G
Q
T
P
L
M
G
R
S
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.1
N.A.
76.4
N.A.
73.6
27.7
N.A.
30.1
23.8
47.8
32.4
N.A.
N.A.
N.A.
N.A.
22.3
Protein Similarity:
100
48.2
N.A.
82.9
N.A.
81.9
43.9
N.A.
44.7
42.6
62.4
51.2
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
0
N.A.
6.6
N.A.
46.6
6.6
N.A.
0
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
N.A.
13.3
N.A.
53.3
13.3
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
10
10
0
20
20
0
0
10
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
10
10
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
10
0
10
20
0
0
10
0
0
10
0
20
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
20
0
40
0
0
0
0
10
20
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
20
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
20
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
20
10
0
0
10
0
10
10
10
30
0
10
20
% L
% Met:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
30
0
20
20
0
10
0
0
10
20
% P
% Gln:
10
0
0
0
10
10
10
10
20
0
0
0
0
0
10
% Q
% Arg:
0
20
30
10
0
0
10
0
0
10
10
40
20
20
0
% R
% Ser:
0
30
0
10
10
0
0
40
10
0
10
0
20
10
10
% S
% Thr:
0
20
0
0
0
10
10
0
10
0
20
10
10
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _