KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC6
All Species:
2.42
Human Site:
T788
Identified Species:
5.93
UniProt:
Q7Z403
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z403
NP_001120670.1
805
90045
T788
E
E
R
S
R
V
G
T
T
E
E
A
A
A
P
Chimpanzee
Pan troglodytes
XP_001153587
647
75381
S631
H
L
G
E
H
D
G
S
L
D
L
R
F
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540460
783
87776
K766
I
S
N
E
G
E
D
K
I
F
L
I
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN60
810
90527
D787
S
R
P
G
R
T
Q
D
A
T
E
P
P
A
W
Rat
Rattus norvegicus
Q5M7W4
965
110699
L930
A
N
P
S
T
L
V
L
E
R
R
E
V
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
S799
S
A
I
L
T
H
Q
S
S
E
K
R
N
A
D
Chicken
Gallus gallus
Q5YCC5
735
84359
K716
E
A
Q
K
N
S
G
K
P
Q
K
A
R
K
L
Frog
Xenopus laevis
NP_001085652
725
84100
R709
N
Q
H
H
S
Q
Q
R
K
A
P
L
F
Q
G
Zebra Danio
Brachydanio rerio
XP_689991
670
76642
Q654
Y
S
P
Q
E
F
D
Q
T
T
Y
Y
N
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
N799
K
L
G
I
T
N
P
N
D
S
V
V
F
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.1
N.A.
76.4
N.A.
73.6
27.7
N.A.
30.1
23.8
47.8
32.4
N.A.
N.A.
N.A.
N.A.
22.3
Protein Similarity:
100
48.2
N.A.
82.9
N.A.
81.9
43.9
N.A.
44.7
42.6
62.4
51.2
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
6.6
N.A.
0
N.A.
20
6.6
N.A.
13.3
20
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
N.A.
0
N.A.
20
13.3
N.A.
33.3
40
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
0
0
0
0
10
10
0
20
10
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
20
10
10
10
0
0
0
0
10
% D
% Glu:
20
10
0
20
10
10
0
0
10
20
20
10
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
30
0
0
% F
% Gly:
0
0
20
10
10
0
30
0
0
0
0
0
0
0
10
% G
% His:
10
0
10
10
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
20
10
0
20
0
0
20
0
% K
% Leu:
0
20
0
10
0
10
0
10
10
0
20
10
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
10
0
10
10
0
10
0
0
0
0
30
0
20
% N
% Pro:
0
0
30
0
0
0
10
0
10
0
10
10
10
10
10
% P
% Gln:
0
10
10
10
0
10
30
10
0
10
0
0
0
10
10
% Q
% Arg:
0
10
10
0
20
0
0
10
0
10
10
20
10
10
10
% R
% Ser:
20
20
0
20
10
10
0
20
10
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
30
10
0
10
20
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _