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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC6
All Species:
5.76
Human Site:
Y101
Identified Species:
14.07
UniProt:
Q7Z403
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z403
NP_001120670.1
805
90045
Y101
R
G
A
I
I
S
Q
Y
Y
N
R
T
V
Q
L
Chimpanzee
Pan troglodytes
XP_001153587
647
75381
I10
S
R
D
R
I
K
A
I
R
N
Q
P
R
T
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540460
783
87776
A101
T
I
G
R
S
R
G
A
I
I
S
Q
Y
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN60
810
90527
Y100
R
G
A
I
I
S
Q
Y
Y
N
R
T
V
R
L
Rat
Rattus norvegicus
Q5M7W4
965
110699
H118
D
F
Q
S
E
S
Y
H
P
D
L
S
M
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
D129
P
D
S
R
E
N
T
D
F
Q
D
K
P
N
Y
Chicken
Gallus gallus
Q5YCC5
735
84359
A95
W
E
L
P
F
S
I
A
E
K
R
D
S
Q
Q
Frog
Xenopus laevis
NP_001085652
725
84100
S89
L
L
K
S
L
P
L
S
L
N
V
K
R
E
L
Zebra Danio
Brachydanio rerio
XP_689991
670
76642
E34
E
V
E
N
N
T
S
E
L
V
S
D
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
I124
S
N
A
E
A
D
E
I
H
E
R
E
I
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.1
N.A.
76.4
N.A.
73.6
27.7
N.A.
30.1
23.8
47.8
32.4
N.A.
N.A.
N.A.
N.A.
22.3
Protein Similarity:
100
48.2
N.A.
82.9
N.A.
81.9
43.9
N.A.
44.7
42.6
62.4
51.2
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
13.3
N.A.
0
N.A.
93.3
6.6
N.A.
0
20
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
N.A.
0
N.A.
100
40
N.A.
20
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
10
0
10
20
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
10
0
10
0
10
10
20
0
0
10
% D
% Glu:
10
10
10
10
20
0
10
10
10
10
0
10
0
20
0
% E
% Phe:
0
10
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
20
10
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
30
0
10
20
10
10
0
0
10
10
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
10
0
20
0
0
0
% K
% Leu:
10
10
10
0
10
0
10
0
20
0
10
0
10
0
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
10
0
10
10
10
0
0
0
40
0
0
0
10
10
% N
% Pro:
10
0
0
10
0
10
0
0
10
0
0
10
10
0
10
% P
% Gln:
0
0
10
0
0
0
20
0
0
10
10
10
0
20
10
% Q
% Arg:
20
10
0
30
0
10
0
0
10
0
40
0
20
10
0
% R
% Ser:
20
0
10
20
10
40
10
10
0
0
20
10
10
10
0
% S
% Thr:
10
0
0
0
0
10
10
0
0
0
0
20
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
10
0
20
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
20
20
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _