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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC6
All Species:
3.33
Human Site:
Y775
Identified Species:
8.15
UniProt:
Q7Z403
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z403
NP_001120670.1
805
90045
Y775
I
N
K
L
H
S
I
Y
E
R
K
E
R
E
E
Chimpanzee
Pan troglodytes
XP_001153587
647
75381
E618
V
L
E
R
R
E
V
E
Q
Q
G
S
L
H
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540460
783
87776
C753
K
G
Q
R
R
V
M
C
L
L
K
E
Q
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN60
810
90527
Y774
I
N
K
L
H
S
V
Y
E
E
E
G
R
S
R
Rat
Rattus norvegicus
Q5M7W4
965
110699
Q917
I
E
K
L
T
K
L
Q
D
I
E
R
R
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
Q786
L
E
K
L
R
K
L
Q
E
T
R
N
K
S
A
Chicken
Gallus gallus
Q5YCC5
735
84359
L703
E
S
R
D
K
L
F
L
L
E
K
L
S
E
A
Frog
Xenopus laevis
NP_001085652
725
84100
E696
N
R
L
H
S
F
Y
E
K
R
S
T
E
N
Q
Zebra Danio
Brachydanio rerio
XP_689991
670
76642
R641
L
Q
N
I
Q
R
Q
R
R
E
I
A
S
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
I786
L
R
M
L
Q
E
A
I
K
K
R
N
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.1
N.A.
76.4
N.A.
73.6
27.7
N.A.
30.1
23.8
47.8
32.4
N.A.
N.A.
N.A.
N.A.
22.3
Protein Similarity:
100
48.2
N.A.
82.9
N.A.
81.9
43.9
N.A.
44.7
42.6
62.4
51.2
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
0
N.A.
13.3
N.A.
60
26.6
N.A.
20
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
N.A.
33.3
N.A.
73.3
46.6
N.A.
46.6
26.6
20
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
20
10
0
0
20
0
20
30
30
20
20
10
20
10
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
10
20
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
30
0
0
10
0
0
10
10
0
10
10
0
0
10
0
% I
% Lys:
10
0
40
0
10
20
0
0
20
10
30
0
20
10
0
% K
% Leu:
30
10
10
50
0
10
20
10
20
10
0
10
10
0
20
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
20
10
0
0
0
0
0
0
0
0
20
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
0
20
0
10
20
10
10
0
0
10
0
10
% Q
% Arg:
0
20
10
20
30
10
0
10
10
20
20
10
30
0
10
% R
% Ser:
0
10
0
0
10
20
0
0
0
0
10
10
20
20
20
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% T
% Val:
10
0
0
0
0
10
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
20
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _