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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC4
All Species:
13.33
Human Site:
S676
Identified Species:
32.59
UniProt:
Q7Z404
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z404
NP_001138775.1
712
79208
S676
Y
T
V
A
L
A
N
S
Y
G
R
L
I
S
E
Chimpanzee
Pan troglodytes
XP_001163927
1299
143450
S1263
Y
T
V
A
L
A
N
S
Y
G
R
L
I
S
E
Rhesus Macaque
Macaca mulatta
XP_001082188
743
83645
S707
Y
T
V
A
R
A
N
S
Y
G
R
L
I
S
E
Dog
Lupus familis
XP_541427
1041
115676
S1002
Y
T
L
A
L
A
N
S
Y
G
R
L
V
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQ65
694
77348
C658
Y
T
V
A
L
A
N
C
Y
G
R
L
I
S
E
Rat
Rattus norvegicus
Q496Z4
698
78193
C662
Y
T
V
A
L
A
N
C
Y
G
R
L
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509221
768
89299
A674
Y
F
V
A
L
A
G
A
H
R
R
V
V
E
Q
Chicken
Gallus gallus
Q5YCC5
735
84359
A681
Y
F
I
A
L
A
G
A
H
K
R
V
V
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664983
732
83100
V657
Y
V
S
A
L
T
S
V
H
G
K
S
V
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395471
756
87723
A705
Y
Y
Y
A
V
S
I
A
N
K
H
M
V
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
61.2
53.7
N.A.
73.7
75
N.A.
34.5
37.1
N.A.
38.2
N.A.
N.A.
28.8
N.A.
N.A.
Protein Similarity:
100
53.7
66.8
58.7
N.A.
84.2
85.2
N.A.
52.9
56.5
N.A.
55
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
40
33.3
N.A.
26.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
73.3
73.3
N.A.
60
N.A.
N.A.
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
80
0
30
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
60
% E
% Phe:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
20
0
0
70
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
30
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
50
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% K
% Leu:
0
0
10
0
80
0
0
0
0
0
0
60
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
60
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
80
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
10
40
0
0
0
10
0
60
0
% S
% Thr:
0
60
0
0
0
10
0
0
0
0
0
0
0
10
0
% T
% Val:
0
10
60
0
10
0
0
10
0
0
0
20
50
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
10
10
0
0
0
0
0
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _