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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC4
All Species:
1.52
Human Site:
S9
Identified Species:
3.7
UniProt:
Q7Z404
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z404
NP_001138775.1
712
79208
S9
E
E
N
P
T
L
E
S
E
A
W
G
S
S
R
Chimpanzee
Pan troglodytes
XP_001163927
1299
143450
P124
E
V
S
R
S
L
W
P
R
L
R
G
N
S
S
Rhesus Macaque
Macaca mulatta
XP_001082188
743
83645
N28
Y
D
Y
E
T
I
R
N
I
D
C
Y
G
T
D
Dog
Lupus familis
XP_541427
1041
115676
K24
P
I
G
F
L
F
K
K
A
G
P
G
L
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQ65
694
77348
S12
G
Q
S
P
A
C
S
S
S
R
K
A
R
T
G
Rat
Rattus norvegicus
Q496Z4
698
78193
W9
E
E
S
P
R
E
A
W
A
Q
F
P
A
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509221
768
89299
A10
E
A
E
A
D
I
F
A
P
E
M
D
S
L
T
Chicken
Gallus gallus
Q5YCC5
735
84359
L10
E
F
G
A
G
A
E
L
P
G
W
V
T
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664983
732
83100
V9
E
L
R
E
F
N
D
V
V
H
P
P
P
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395471
756
87723
A22
Q
G
W
E
E
A
G
A
E
F
Y
Q
E
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
61.2
53.7
N.A.
73.7
75
N.A.
34.5
37.1
N.A.
38.2
N.A.
N.A.
28.8
N.A.
N.A.
Protein Similarity:
100
53.7
66.8
58.7
N.A.
84.2
85.2
N.A.
52.9
56.5
N.A.
55
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
13.3
N.A.
13.3
20
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
46.6
33.3
20
N.A.
33.3
40
N.A.
26.6
26.6
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
20
10
20
10
20
20
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
10
0
0
10
0
10
0
10
10
% D
% Glu:
60
20
10
30
10
10
20
0
20
10
0
0
10
10
0
% E
% Phe:
0
10
0
10
10
10
10
0
0
10
10
0
0
0
0
% F
% Gly:
10
10
20
0
10
0
10
0
0
20
0
30
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
20
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% K
% Leu:
0
10
0
0
10
20
0
10
0
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
10
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
30
0
0
0
10
20
0
20
20
10
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
10
10
10
0
10
0
10
10
10
0
10
0
20
% R
% Ser:
0
0
30
0
10
0
10
20
10
0
0
0
20
30
30
% S
% Thr:
0
0
0
0
20
0
0
0
0
0
0
0
10
20
10
% T
% Val:
0
10
0
0
0
0
0
10
10
0
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
10
10
0
0
20
0
0
10
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
0
10
10
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _